Background: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA)-BFNx011502 and carbamazepine-induced SJS in Han Chinese patients. European studies suggested that HLA-BFNx011502 is not a universal marker but is ethnicity-specific for Asians. Aim: To study the association between HLA-BFNx011502 and carbamazepine-induced SJS in Indian patients. Methods: Eight individuals who fulfilled the diagnostic criteria of SJS induced by carbamazepine were identified and HLA-B molecular typing was performed. HLA-B genotyping was carried out by polymerase chain reaction usin...
AbstractBackgroundRecent study demonstrated that HLA-B*1502 was a common risk allele in aromatic ant...
Background: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a signi...
Cutaneous adverse drug reaction (cADR) has limited epidemiological data in India. The older antiepil...
Background: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous react...
AbstractPrevious studies have found a strong association between HLA-B*1502 and carbamazepine-induce...
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Ste...
Genetic predisposition to carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epide...
[[abstract]]BACKGROUND Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cau...
BACKGROUND: Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopap...
Background: Although the US FDA recommends screening for HLA-B*1502 allele in most of Asian ancestry...
Background: Carbamazepine (CBZ) is a drug with an important role in treatment of epilepsy, neuropath...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), a type of severe cutaneous adv...
Recently, the USA FDA has made a labeling change to the drug information contained in carbamazepine....
Stevens-Johnson syndrome and toxic epidermal necrolysis is a very rare but lifethreatening form of c...
we observed a high incidence of carbamazepine (CBZ)-induced severe cutaneous adverse drug reactions ...
AbstractBackgroundRecent study demonstrated that HLA-B*1502 was a common risk allele in aromatic ant...
Background: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a signi...
Cutaneous adverse drug reaction (cADR) has limited epidemiological data in India. The older antiepil...
Background: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous react...
AbstractPrevious studies have found a strong association between HLA-B*1502 and carbamazepine-induce...
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Ste...
Genetic predisposition to carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epide...
[[abstract]]BACKGROUND Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cau...
BACKGROUND: Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopap...
Background: Although the US FDA recommends screening for HLA-B*1502 allele in most of Asian ancestry...
Background: Carbamazepine (CBZ) is a drug with an important role in treatment of epilepsy, neuropath...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), a type of severe cutaneous adv...
Recently, the USA FDA has made a labeling change to the drug information contained in carbamazepine....
Stevens-Johnson syndrome and toxic epidermal necrolysis is a very rare but lifethreatening form of c...
we observed a high incidence of carbamazepine (CBZ)-induced severe cutaneous adverse drug reactions ...
AbstractBackgroundRecent study demonstrated that HLA-B*1502 was a common risk allele in aromatic ant...
Background: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a signi...
Cutaneous adverse drug reaction (cADR) has limited epidemiological data in India. The older antiepil...