Add to ORKGRhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood, with two predominant histologic subtypes: embryonal and alveolar. These histologies display distinct clinical courses, and despite refinements in dose and duration of multimodality therapy, the 5-year overall survival of patients diagnosed with metastatic RMS remains <30%. Thus, there is an urgent need to define novel targets for therapeutic intervention. Interrogation of cancer cell signal transduction pathways that regulate the pathogenic behaviours of tumor cells has been successful in defining targets in numerous tumor types. These have ultimately yielded clinically-relevant drugs that have improved the disease-free and overall survival of patients diagnosed...
BACKGROUND: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
To identify novel signaling pathways necessary for rhabdomyosarcoma (RMS) survival, we performed a l...
[eng] Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. R...
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood, with two predominant his...
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The t...
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The t...
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and young adults. Several ...
Background: Integrin-linked kinase (ILK) is a potent intracellular kinase involved in the regulation...
The pediatric sarcoma alveolar rhabdomyosarcoma (ARMS) is highly aggressive with a poor prognosis fo...
Background:The integrin-linked kinase (ILK) is a protein kinase involved in the regulation of pathog...
Background/Aims: Rhabdomyosarcoma, the most common pediatric soft tissue sarcoma, may show an intrin...
Background: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
Background: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
Item does not contain fulltextTargeted therapies have revolutionized cancer treatment; however, prog...
Thesis (Ph.D.)--University of Washington, 2020Rhabdomyosarcoma (RMS) is the most common soft tissue ...
BACKGROUND: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
To identify novel signaling pathways necessary for rhabdomyosarcoma (RMS) survival, we performed a l...
[eng] Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. R...
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood, with two predominant his...
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The t...
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The t...
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and young adults. Several ...
Background: Integrin-linked kinase (ILK) is a potent intracellular kinase involved in the regulation...
The pediatric sarcoma alveolar rhabdomyosarcoma (ARMS) is highly aggressive with a poor prognosis fo...
Background:The integrin-linked kinase (ILK) is a protein kinase involved in the regulation of pathog...
Background/Aims: Rhabdomyosarcoma, the most common pediatric soft tissue sarcoma, may show an intrin...
Background: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
Background: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
Item does not contain fulltextTargeted therapies have revolutionized cancer treatment; however, prog...
Thesis (Ph.D.)--University of Washington, 2020Rhabdomyosarcoma (RMS) is the most common soft tissue ...
BACKGROUND: Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and...
To identify novel signaling pathways necessary for rhabdomyosarcoma (RMS) survival, we performed a l...
[eng] Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. R...