Add to ORKGClonal culture is crucial for experimental protocols that require growth or selection of pure populations of cells. Currently, there is no method for deriving neural stem cells (NSCs) clonally from single human embryonic stem cells (hESCs). Bulk derivation of neural progenitors from hESCs for cell therapies can lead to a host of problems including incomplete differentiation leading to proliferation of tumorigenic clusters in vivo. Clonal derivation allows for the screening and selection of only the most suitable cells for culture and expansion. We have developed a clonal, serum free method of generating NSCs and their progenitors directly from hESCs with an efficiency of 1.6%. The NSC colony-forming cell was identified as a TRA-1-60-/SS...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
Neural stem cells (NSCs) are potential sources for cell therapy of neurodegenerative diseases and fo...
Clonal culture is crucial for experimental protocols that require growth or selection of pure popula...
Human embryonic stem cells (hESCs) have extensive self-renewal capacity and are competent to differe...
<div><p>Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to dif...
Neural differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiP...
Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to differentia...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Lukovic, Dunja et al.Neural differentiation of human embryonic stem cells (hESCs) and induced plurip...
The availability of human neuronal progenitors (hNPs) in high purity would greatly facilitate neuron...
The availability of human neuronal progenitors (hNPs) in high purity would greatly facilitate neuron...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Neural crest cells (NCCs) arise between neural and non-neural ectoderm and migrate to form a variety...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
Neural stem cells (NSCs) are potential sources for cell therapy of neurodegenerative diseases and fo...
Clonal culture is crucial for experimental protocols that require growth or selection of pure popula...
Human embryonic stem cells (hESCs) have extensive self-renewal capacity and are competent to differe...
<div><p>Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to dif...
Neural differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiP...
Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to differentia...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Lukovic, Dunja et al.Neural differentiation of human embryonic stem cells (hESCs) and induced plurip...
The availability of human neuronal progenitors (hNPs) in high purity would greatly facilitate neuron...
The availability of human neuronal progenitors (hNPs) in high purity would greatly facilitate neuron...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Robust strategies for developing patient-specific, human, induced pluripotent stem cell (iPSC)-based...
Neural crest cells (NCCs) arise between neural and non-neural ectoderm and migrate to form a variety...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner i...
Neural stem cells (NSCs) are potential sources for cell therapy of neurodegenerative diseases and fo...