The aim of this thesis was to elucidate the role of carbonic anhydrase (CA) in the modulation of central pH/CO2-sensitive fictive breathing (measured using in vitro brainstem-spinal cord preparations) in leopard frogs (Rana pipiens) following exposure to chronic hypercapnia (CHC) and chronic hypoxia (CH). CHC caused an augmentation in fictive breathing compared to the controls (normoxic normocapnic). Addition of acetazolamide (ACTZ), a cell-permeant CA inhibitor, to the superfusate reduced fictive breathing in the controls and abolished the CHC-induced augmentation of fictive breathing. ACTZ had no effect on preparations taken from frogs exposed to CH. Addition of bovine CA to the superfusate did not alter fictive breathing in any group, su...
We test the hypothesis that central respiratory CO2/pH chemosensitivity, recorded from isolated brai...
The locus coeruleus (LC) in the brainstem senses alterations in CO2/pH and influences ventilatory ad...
AbstractAnuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and ...
The aim of this thesis was to elucidate the role of carbonic anhydrase (CA) in the modulation of cen...
This study examined the effects of temperature and chronic hypoxia (CH) on pH/CO2- sensitive fictive...
Specimens of Bufo marinus were exposed to aerial and aquatic hypercapnia (5 % CO2) in a closed, wate...
The locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. This nucleus is ...
Toads (Bufo marinus) were exposed to environmental hypercapnia of 5 % CO2 in air, and extracellular ...
The low temperatures encountered by overwintering frogs result in a large downregulation of metaboli...
The nucleus isthmi (NI) is a mesencephalic structure of the amphibian brain. It has been reported th...
Digestion affects acid-base status, because the net transfer of HCl from the blood to the stomach lu...
Cutaneous CO2 excretion is reduced as the skin dries during dehydration but an increase in breath fr...
Anuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and to exhib...
The ontogeny of ventilatory control was studied in developing bullfrogs (Rana catesbeiana) by measur...
We investigated the effects of hypercapnia on intracellular acid-base regulation in brain and liver ...
We test the hypothesis that central respiratory CO2/pH chemosensitivity, recorded from isolated brai...
The locus coeruleus (LC) in the brainstem senses alterations in CO2/pH and influences ventilatory ad...
AbstractAnuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and ...
The aim of this thesis was to elucidate the role of carbonic anhydrase (CA) in the modulation of cen...
This study examined the effects of temperature and chronic hypoxia (CH) on pH/CO2- sensitive fictive...
Specimens of Bufo marinus were exposed to aerial and aquatic hypercapnia (5 % CO2) in a closed, wate...
The locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. This nucleus is ...
Toads (Bufo marinus) were exposed to environmental hypercapnia of 5 % CO2 in air, and extracellular ...
The low temperatures encountered by overwintering frogs result in a large downregulation of metaboli...
The nucleus isthmi (NI) is a mesencephalic structure of the amphibian brain. It has been reported th...
Digestion affects acid-base status, because the net transfer of HCl from the blood to the stomach lu...
Cutaneous CO2 excretion is reduced as the skin dries during dehydration but an increase in breath fr...
Anuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and to exhib...
The ontogeny of ventilatory control was studied in developing bullfrogs (Rana catesbeiana) by measur...
We investigated the effects of hypercapnia on intracellular acid-base regulation in brain and liver ...
We test the hypothesis that central respiratory CO2/pH chemosensitivity, recorded from isolated brai...
The locus coeruleus (LC) in the brainstem senses alterations in CO2/pH and influences ventilatory ad...
AbstractAnuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and ...