grantor: University of TorontoImage analysis and image reconstruction processes are critical in obtaining protein three-dimensional structures after their two-dimensional images are acquired by electron microscopy. This thesis reports my work on improving several aspects in this field. The angular distribution dependent (ADD) filtering algorithm is developed for an improved accuracy in three-dimensional reconstruction by the filtered backprojection method. The phase difference analysis (PDA) is employed to enhance the peaks in the sinogram correlation functions for a more accurate determination of projection directions for the randomly orientated protein particles. These improvements will result in a higher achievable resolution i...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
Dramatic improvements in experimental methods and computational techniques have revolutionized three...
grantor: University of TorontoImage analysis and image reconstruction processes are critic...
Three-dimensional structures have recently been determined by electron crystallography at a resoluti...
Three-dimensional structures have recently been determined by electron crystallography at a resoluti...
Three dimensional Electron Microscopy (EM) and in particular single particle reconstruction using cr...
SummaryDynamic macromolecular assemblies, such as ribosomes, viruses, and muscle protein complexes, ...
Dark-field electron microscopy has the potential of providing high resolution images of biological m...
Dark-field electron microscopy has the potential of providing high resolution images of biological m...
Three-dimensional (3D) reconstruction of a single protein molecule is essential for understanding th...
One of the next great challenges of cell biology is the determination of the enormous number of prot...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
Dramatic improvements in experimental methods and computational techniques have revolutionized three...
grantor: University of TorontoImage analysis and image reconstruction processes are critic...
Three-dimensional structures have recently been determined by electron crystallography at a resoluti...
Three-dimensional structures have recently been determined by electron crystallography at a resoluti...
Three dimensional Electron Microscopy (EM) and in particular single particle reconstruction using cr...
SummaryDynamic macromolecular assemblies, such as ribosomes, viruses, and muscle protein complexes, ...
Dark-field electron microscopy has the potential of providing high resolution images of biological m...
Dark-field electron microscopy has the potential of providing high resolution images of biological m...
Three-dimensional (3D) reconstruction of a single protein molecule is essential for understanding th...
One of the next great challenges of cell biology is the determination of the enormous number of prot...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
International audienceThree-dimensional (3D) structure of a wide range of biological macromolecular ...
Dramatic improvements in experimental methods and computational techniques have revolutionized three...