grantor: University of TorontoThe free-living soil nematode 'Caenorhabditis elegans' exists in nature as one of two possible sexes, the male or the self-fertile hermaphrodite. Most genes controlling sex determination in 'C. elegans ' have been cloned and sequenced. These genes have been ordered into a signal transduction cascade based on their epistatic interactions. I have uncovered evidence supporting a direct interaction between the proteins encoded by two of the genes in the pathway, 'her-1' and 'tra-2'. This was achieved through binding assays involving immunofluorescent and immunoblotting techniques. The proposed interaction sheds light on the possible mechanisms by which HER-1 negatively regulates the activity of TRA-2A in...
SummaryThe self-fertile hermaphrodites of C. elegans and C. briggsae evolved from female ancestors b...
Sex determination has long intrigued evolutionists, geneticists, and developmental biologists in a s...
The nematode Caenorhabditis elegans has two sexes, hermaphrodites and males. Hermaphrodites normally...
grantor: University of TorontoThe free-living soil nematode 'Caenorhabditis elegans' exis...
grantor: University of TorontoMale development in the nematode 'Caenorhabditis elegans' re...
grantor: University of TorontoMale sexual development in the nematode 'Caenorhabditis eleg...
AbstractUnlike many features of metazoan development, sex determination is not widely conserved amon...
The Caenorhabditis elegans sex-determining gene, tra-2, promotes female development in XX animals. I...
Most species of the nematode genus Caenorhabditis reproduce through males and females. C. elegans an...
SummaryTRA-1A is the sole representative in Caenorhabditis elegans of the Gli transcription factor f...
The nematode Caenorhabditis elegans has two sexes: males and hermaphrodites. Hermaphrodites are esse...
Sex determination i Caenorhabditis elegans is a problem that lends itself to investigation by a &quo...
Most nematodes have XO male/XX female sex deter-mination. C. elegans is anomalous, having XX her-map...
University of Minnesota Ph.D. dissertation. December 2013. Major: Molecular, Cellular, Developmental...
Sex-determining genes have been identified in many animals, but how they impose sex specificity on d...
SummaryThe self-fertile hermaphrodites of C. elegans and C. briggsae evolved from female ancestors b...
Sex determination has long intrigued evolutionists, geneticists, and developmental biologists in a s...
The nematode Caenorhabditis elegans has two sexes, hermaphrodites and males. Hermaphrodites normally...
grantor: University of TorontoThe free-living soil nematode 'Caenorhabditis elegans' exis...
grantor: University of TorontoMale development in the nematode 'Caenorhabditis elegans' re...
grantor: University of TorontoMale sexual development in the nematode 'Caenorhabditis eleg...
AbstractUnlike many features of metazoan development, sex determination is not widely conserved amon...
The Caenorhabditis elegans sex-determining gene, tra-2, promotes female development in XX animals. I...
Most species of the nematode genus Caenorhabditis reproduce through males and females. C. elegans an...
SummaryTRA-1A is the sole representative in Caenorhabditis elegans of the Gli transcription factor f...
The nematode Caenorhabditis elegans has two sexes: males and hermaphrodites. Hermaphrodites are esse...
Sex determination i Caenorhabditis elegans is a problem that lends itself to investigation by a &quo...
Most nematodes have XO male/XX female sex deter-mination. C. elegans is anomalous, having XX her-map...
University of Minnesota Ph.D. dissertation. December 2013. Major: Molecular, Cellular, Developmental...
Sex-determining genes have been identified in many animals, but how they impose sex specificity on d...
SummaryThe self-fertile hermaphrodites of C. elegans and C. briggsae evolved from female ancestors b...
Sex determination has long intrigued evolutionists, geneticists, and developmental biologists in a s...
The nematode Caenorhabditis elegans has two sexes, hermaphrodites and males. Hermaphrodites normally...