Add to ORKGgrantor: University of Torontop53 tumour suppressor gene mutations and associated nuclear accumulation of altered p53 protein are frequently observed in lung cancers. A study was carried out to investigate the relationship between smoking and p53, and their association with clinicopathologic features and prognosis in non-small cell lung cancer (NSCLC). Meta-analyses were performed and found associations between p53 alterations (gene and/or protein) and squamous cell histology, tumour size and extension (T), nodal status (N), stage, differentiation and smoking history. In the Mount Sinai Hospital Study (MSH Study) (Toronto), 119 stage I-III NSCLC patients were followed prospectively. For 111 patients, tumour p53 protein accumulatio...
p53 is a tumor suppressor gene, located in the short arm of chromosome 17, which encodes for a nucle...
Although epidemiological studies of the relationship between cigarette smoking and colorectal cancer...
Lung cancer (LCa) is the leading cause of death by cancer in men. Genetic and environmental factors ...
grantor: University of Torontop53 tumour suppressor gene mutations and associated nuclear ...
p53 mutations are among the most frequent genetic alterations reported in human lung cancer. Althoug...
For the p53 Special Issue Of the various genetic alterations in lung cancer, the abnormalities of th...
ABSTRACT Epidemiology data have established that smoking is a prime threat for the cancers, largely ...
TP53 mutations are common in lung cancers of smokers, with high prevalence of G:C-to-T:A transversio...
ABSTRACT Epidemiology data have established that smoking is a prime threat for the cancers, largely ...
This issue marks the 50th anniversary of the release of the U.S. Surgeon General's Report on Sm...
P53 gene mutations are the most common genetic changes reported in human lung cancer. Although the p...
It has been proposed that the patterns of mutations in the p53 tumor suppressor gene will provide cl...
The use of molecular biomarkers, such as mutations in the p53 gene, has raised expectations for impr...
Background: Non–small cell lung cancer (NSCLC) with TP53 mutations has a worse prognosis. It was gen...
Background: The p53 gene is frequently mutated in non-small-cell lung cancer (NSCLC); however, the e...
p53 is a tumor suppressor gene, located in the short arm of chromosome 17, which encodes for a nucle...
Although epidemiological studies of the relationship between cigarette smoking and colorectal cancer...
Lung cancer (LCa) is the leading cause of death by cancer in men. Genetic and environmental factors ...
grantor: University of Torontop53 tumour suppressor gene mutations and associated nuclear ...
p53 mutations are among the most frequent genetic alterations reported in human lung cancer. Althoug...
For the p53 Special Issue Of the various genetic alterations in lung cancer, the abnormalities of th...
ABSTRACT Epidemiology data have established that smoking is a prime threat for the cancers, largely ...
TP53 mutations are common in lung cancers of smokers, with high prevalence of G:C-to-T:A transversio...
ABSTRACT Epidemiology data have established that smoking is a prime threat for the cancers, largely ...
This issue marks the 50th anniversary of the release of the U.S. Surgeon General's Report on Sm...
P53 gene mutations are the most common genetic changes reported in human lung cancer. Although the p...
It has been proposed that the patterns of mutations in the p53 tumor suppressor gene will provide cl...
The use of molecular biomarkers, such as mutations in the p53 gene, has raised expectations for impr...
Background: Non–small cell lung cancer (NSCLC) with TP53 mutations has a worse prognosis. It was gen...
Background: The p53 gene is frequently mutated in non-small-cell lung cancer (NSCLC); however, the e...
p53 is a tumor suppressor gene, located in the short arm of chromosome 17, which encodes for a nucle...
Although epidemiological studies of the relationship between cigarette smoking and colorectal cancer...
Lung cancer (LCa) is the leading cause of death by cancer in men. Genetic and environmental factors ...