A direct and fast liquid chromatographic–electrospray ionization-tandem mass spectrometric (LC–ESI-MS–MS) method is described for the determination of 3-O-glucuronides of E- and Z-entacapone, nitecapone and tolcapone and 1-O- and 2-O-glucuronides of 4-nitrocatechol in urine. p-Nitrophenyl β-d-glucuronide was used as internal standard. Spiked urine samples were prepared by solid-phase extraction and analysed by isocratic LC–ESI-MS–MS in negative ion mode. The ESI mass spectra showed an abundant deprotonated molecule [M–H]−, which was chosen as precursor ion. Collisionally induced dissociation of [M–H]− in MS–MS resulted in the loss of neutral glucuronide moiety and in the appearance of an intense negatively charged drug molecule, which was c...
Abstractβ-D-ethylglucuronide (EtG) is a stable Phase II metabolite of ethanol which can be detected ...
AbstractThe mass spectrometric (MS) and tandem mass spectrometric (MS/MS) behavior of six nitrocatec...
An alternative liquid chromatography-mass spectrometry (LC-MS) method based on no discharge (ND) atm...
A direct and fast liquid chromatographic–electrospray ionization-tandem mass spectrometric (LC–ESI-M...
A liquid chromatography atmospheric pressure electrospray mass spectrometry (ESI-LC/MS) system was ...
A method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the direct quantific...
This paper describes a liquid chromatographic/ tandem mass spectrometric (LC/MS–MS) method specifica...
This paper presents a general screening method, based on liquid chromatography/mass spectrometry (LC...
A liquid chromatography/electrospray tandem mass spectrometry (LC/ESI-MS/MS) method for the determin...
Liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method for sim...
The method for simultaneous determination and confirmation of illicit drugs (e.g., methamphetamine, ...
Determination of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1- ...
A fast liquid chromatographic/mass spectrometric (LC/MS/MS) screening method for the detection, in u...
This thesis presents novel approaches for structural investigation of glucuronides using chemical de...
This study presents a fast multi-analyte screening method specifically developed for the detection o...
Abstractβ-D-ethylglucuronide (EtG) is a stable Phase II metabolite of ethanol which can be detected ...
AbstractThe mass spectrometric (MS) and tandem mass spectrometric (MS/MS) behavior of six nitrocatec...
An alternative liquid chromatography-mass spectrometry (LC-MS) method based on no discharge (ND) atm...
A direct and fast liquid chromatographic–electrospray ionization-tandem mass spectrometric (LC–ESI-M...
A liquid chromatography atmospheric pressure electrospray mass spectrometry (ESI-LC/MS) system was ...
A method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the direct quantific...
This paper describes a liquid chromatographic/ tandem mass spectrometric (LC/MS–MS) method specifica...
This paper presents a general screening method, based on liquid chromatography/mass spectrometry (LC...
A liquid chromatography/electrospray tandem mass spectrometry (LC/ESI-MS/MS) method for the determin...
Liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method for sim...
The method for simultaneous determination and confirmation of illicit drugs (e.g., methamphetamine, ...
Determination of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1- ...
A fast liquid chromatographic/mass spectrometric (LC/MS/MS) screening method for the detection, in u...
This thesis presents novel approaches for structural investigation of glucuronides using chemical de...
This study presents a fast multi-analyte screening method specifically developed for the detection o...
Abstractβ-D-ethylglucuronide (EtG) is a stable Phase II metabolite of ethanol which can be detected ...
AbstractThe mass spectrometric (MS) and tandem mass spectrometric (MS/MS) behavior of six nitrocatec...
An alternative liquid chromatography-mass spectrometry (LC-MS) method based on no discharge (ND) atm...