Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics

We present an interdisciplinary approach that allows for the evaluation of nanoparticle cytotoxicity at the single-cell level. By combining single-cell microfluidics with nanoparticle chemistry, real-time and high-throughput multimodal imaging of cellular interactions with functionalised gold nanorods was successfully achieved. The integration of such techniques into tools for high-resolution cell monitoring and drug screening has, to the best of our knowledge, not been reported