152 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.The DNA double helix is stable and rigid, making it an ideal nanoscale construction element. Duplex DNA has been used as a static framework to organize DNA, proteins, or nanoparticles, and dynamic DNA nanomachines have been built. However, assemblies in which DNA controls the intramolecular states of other macromolecules are rare. In this thesis, short (10--20 bp) DNA duplexes are used as structural constraints to control RNA conformation. Based on the X-ray crystal structure of the 160-nucleotide P4--P6 RNA domain of the Tetrahymena group I intron, pairs of sites for attachment of a DNA constraint were chosen rationally. When the DNA constraint is either incompatible or...
ABSTRACT: Over the past three decades DNA has emerged as an exceptional molecular building block for...
Abstract: We have used internal coordinate molecular mechanics calculations to study how the DNA dou...
AbstractBackground: Proteins can force DNA to adopt distorted helical structures that are rarely if ...
152 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.The DNA double helix is stabl...
As the canonical image of molecular biology, the DNA double helix exemplifies stability and structur...
DNA and RNA are large and flexible polymers selected by nature to transmit information. The most com...
University of Minnesota Ph.D. dissertation. April 2012. Major: Chemical Engineering. Advisor: Kevin ...
Thesis: Ph. D. in Medical Engineering and Medical Physics, Harvard-MIT Program in Health Sciences an...
Molecular structure is fundamental for understanding mechanisms of molecular interactions. This appl...
An extensive analysis of structural databases is carried out to investigate the relative flexibility...
Includes bibliographical references (leaves 162-170).Nanotechnology is defined as the technology tha...
The organization of DNA is essential to genetic protection and access and is highly dependent on fac...
AbstractThe structure and flexibility of the RNA duplex has been studied using extended molecular dy...
DNA is used in nature as a biological material of choice to store and transfer genetic information. ...
Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA) are molecules that store and transmit genetic...
ABSTRACT: Over the past three decades DNA has emerged as an exceptional molecular building block for...
Abstract: We have used internal coordinate molecular mechanics calculations to study how the DNA dou...
AbstractBackground: Proteins can force DNA to adopt distorted helical structures that are rarely if ...
152 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.The DNA double helix is stabl...
As the canonical image of molecular biology, the DNA double helix exemplifies stability and structur...
DNA and RNA are large and flexible polymers selected by nature to transmit information. The most com...
University of Minnesota Ph.D. dissertation. April 2012. Major: Chemical Engineering. Advisor: Kevin ...
Thesis: Ph. D. in Medical Engineering and Medical Physics, Harvard-MIT Program in Health Sciences an...
Molecular structure is fundamental for understanding mechanisms of molecular interactions. This appl...
An extensive analysis of structural databases is carried out to investigate the relative flexibility...
Includes bibliographical references (leaves 162-170).Nanotechnology is defined as the technology tha...
The organization of DNA is essential to genetic protection and access and is highly dependent on fac...
AbstractThe structure and flexibility of the RNA duplex has been studied using extended molecular dy...
DNA is used in nature as a biological material of choice to store and transfer genetic information. ...
Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA) are molecules that store and transmit genetic...
ABSTRACT: Over the past three decades DNA has emerged as an exceptional molecular building block for...
Abstract: We have used internal coordinate molecular mechanics calculations to study how the DNA dou...
AbstractBackground: Proteins can force DNA to adopt distorted helical structures that are rarely if ...