Age associated cognitive decline in human and rodents has been linked with decreases in hippocampal neurogenesis and a chronic low grade inflammation in the central nervous system. Physical exercise increases neurogenesis and reverses some cognitive deficits observed in the elderly, but the extent to which dietary supplementation may interact with exercise is unknown. Epigallocatechin gallate (EGCG, a catechin high in green tea) can ameliorate age-related cognitive decline. In addition, β-alanine (β-Ala, a naturally occurring amino acid) may be beneficial against cognitive aging. We hypothesized that exercise (voluntary wheel running, VWR) and dietary supplementation with EGCG (182 mg/kg/d) and β-Ala (417 mg/kg/d) would interact to improve ...
<b><i>Background:</i></b> Aging impairs hippocampal neuroplasticity and hippocampus-related learning...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...
Aging is associated with impaired learning and memory accompanied by reductions in adult hippocampal...
Nutrition and physical exercise can enhance cognitive function but the specific combinations of diet...
D-galactose has been widely used in aging research because of its efficacy in inducing senescence an...
Summary: Hippocampal function is critical for spatial and contextual learning, and its decline with ...
Flavonoid-rich foods have been shown to be effective at reversing age-related deficits in learning a...
We have previously shown that a diet containing epigallocatechin gallate (EGCG) and beta-alanine is ...
We have previously shown that 6 weeks of a diet containing epigallocatechin gallate (EGCG) and beta-...
Ageing is a complex process associated with a decline in organism functions. Ageing affects several ...
AbstractWe investigated the effects of physical exercise and green tea supplementation (associated o...
Aging is associated with cognitive decline in otherwise healthy older adults. As human lifespan incr...
Animal studies showed positive impact of physical activity on cognitive abilities. In animal models,...
Aging leads to sarcopenia and loss of physical function. We examined whether voluntary wheel running...
<b><i>Background:</i></b> Aging impairs hippocampal neuroplasticity and hippocampus-related learning...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...
Aging is associated with impaired learning and memory accompanied by reductions in adult hippocampal...
Nutrition and physical exercise can enhance cognitive function but the specific combinations of diet...
D-galactose has been widely used in aging research because of its efficacy in inducing senescence an...
Summary: Hippocampal function is critical for spatial and contextual learning, and its decline with ...
Flavonoid-rich foods have been shown to be effective at reversing age-related deficits in learning a...
We have previously shown that a diet containing epigallocatechin gallate (EGCG) and beta-alanine is ...
We have previously shown that 6 weeks of a diet containing epigallocatechin gallate (EGCG) and beta-...
Ageing is a complex process associated with a decline in organism functions. Ageing affects several ...
AbstractWe investigated the effects of physical exercise and green tea supplementation (associated o...
Aging is associated with cognitive decline in otherwise healthy older adults. As human lifespan incr...
Animal studies showed positive impact of physical activity on cognitive abilities. In animal models,...
Aging leads to sarcopenia and loss of physical function. We examined whether voluntary wheel running...
<b><i>Background:</i></b> Aging impairs hippocampal neuroplasticity and hippocampus-related learning...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...
Normal aging alters expression of numerous genes within the brain. Some of these transcription chang...