Efficient protocol for reductive amination of aldehydes and ketones with sodium borohydride in an ionic liquid/H<SUB>2</SUB>O system
- Nagaiah, K.
- Naveen Kumar, V.
- Srinivasa Rao, R.
- Reddy, B. V. S.
- Narsaiah, A. V.
- Yadav, J. S.
DOIAbstract
The imines were generated in situ from carbonyl compounds and amines, which undergo smooth reduction with sodium borohydride in an ionic liquid/H<SUB>2</SUB>O solvent system. The reaction conditions were very mild and neutral to afford the corresponding highly functionalized amines in excellent yields
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