Backbone regulation mimicry by β-peptidic foldamers: Formation of a 10-helix in a mixed 6-strand/14-helix conformational pool

Hybrid β-peptide foldamer: Detailed NMR spectroscopy studies have revealed the formation of a new class of 10-helix in hybrid β-peptidic assembly comprised of 6-strand and 14-helical nucleating motifs. These findings show a new means of accessing intermediate secondary structures and also mimic backbone regulations in biomolecules