Deuterium isotope effect on hydrogen bonding

The interaction of phenol and phenol-d with a number of donors of varying basicity has been studied in terms of the equilibrium constants, ΔS0, ΔH0, ΔνOH, and ΔνOD and various aspects of deuterium isotope effects on hydrogen bonding have been discussed. The deuterium isotope effects are found to vary markedly with the basicity of the donor and the results are discussed in terms of the zero point contributions to the KH/KD