The effect of phenobarbital on the rates of the synthesis of the protein and heme moieties of cytochromeP-450 has been studied. For this purpose, cytochrome P-450 has been partially purified as its P-420 derivative and the labeled amino acid incorporation into the protein has been studied after subjecting a partially purified preparation to sodium dodecyl sulfate gel electrophoresis. The incorporation studies into the protein species after sodium dodecyl sulfate gel electrophoresis reveal that the drug primarily accelerates the rate of apoptotein synthesis followed by an increase in the rate of heme synthesis. The messenger for apocytochrome P-450 appears to be fairly stable
In the course of this reaction cycle the heme protein undergoes a series of changes of its coordinat...
"The Cytochrome P450 family serves as the forefront for xenobiotic metabolism in the human body. An ...
The proposed mechanism by which hepatic ALV-synthase mitochondrial levels are regulated is outlined ...
The effect of phenobarbital on the rates of the synthesis of the protein and heme moieties of cytoc...
The effect of phenobarbital on the rates of the synthesis\ud of the protein and heme moieties of cyt...
The mold Neurospora crassa does not accumulate porphyrins in iron deficiency but instead accumulates...
Several substances have been shown to affect hepatic heme synthesis in the rat liver. Phenobarbital ...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
In Neurospora crassa, the activity of δ-aminolevulinate dehydratase, the second and rate-limiting e...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
In Neurospora crassa, the activity of d-aminolevulinate dehydratase, the second and rate-limiting en...
T HE INSERTION OF IRON into protoporphyrin is the final step of a series of reactions in the biosynt...
In Neurospora crassa, the activity of d-aminolevulinate dehydratase, the second and rate-limiting en...
[delta]-Aminolevulinic acid synthetase, the initial and rate limiting step in hepatic heme synthesis...
In the course of this reaction cycle the heme protein undergoes a series of changes of its coordinat...
"The Cytochrome P450 family serves as the forefront for xenobiotic metabolism in the human body. An ...
The proposed mechanism by which hepatic ALV-synthase mitochondrial levels are regulated is outlined ...
The effect of phenobarbital on the rates of the synthesis of the protein and heme moieties of cytoc...
The effect of phenobarbital on the rates of the synthesis\ud of the protein and heme moieties of cyt...
The mold Neurospora crassa does not accumulate porphyrins in iron deficiency but instead accumulates...
Several substances have been shown to affect hepatic heme synthesis in the rat liver. Phenobarbital ...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
In Neurospora crassa, the activity of δ-aminolevulinate dehydratase, the second and rate-limiting e...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
2-Allylisopropylacetamide, a porphyrinogen which decreases the microsomal and cytosolic heme pools, ...
In Neurospora crassa, the activity of d-aminolevulinate dehydratase, the second and rate-limiting en...
T HE INSERTION OF IRON into protoporphyrin is the final step of a series of reactions in the biosynt...
In Neurospora crassa, the activity of d-aminolevulinate dehydratase, the second and rate-limiting en...
[delta]-Aminolevulinic acid synthetase, the initial and rate limiting step in hepatic heme synthesis...
In the course of this reaction cycle the heme protein undergoes a series of changes of its coordinat...
"The Cytochrome P450 family serves as the forefront for xenobiotic metabolism in the human body. An ...
The proposed mechanism by which hepatic ALV-synthase mitochondrial levels are regulated is outlined ...