A stereoselective synthesis of new isofagomine analogues has been achieved from a suitably functionalized cyclopentene intermediate extracted from the norbornyl framework. Double reductive amination or inter- and intramolecular N-alkylations are the key steps in constructing the piperidine ring. Isofagomine derivatives exhibit moderate inhibitory activity in enzyme assays
The syntheses of the polyhydroxylated piperidines deoxygalactonojirimycin 2, homogalactonojirimycins...
The main purpose of this work was the synthesis of polyhydroxylated pyrrolizidines and aza-C-disacch...
- A new expeditious preparation of homochiral (-)-1-azafagomine, and (+)-5-epi-1-azafagomine has bee...
A stereoselective synthesis of new isofagomine analogues has been achieved from a suitably functiona...
A new synthesis of deoxynojirimycin (DNJ) analogues (galacto- and altrose configuration) has been ac...
This comprehensive review deals with the synthesis of 1-azafagomine, analogs, and derivatives having...
New hydroxy azepanes with an additional hydroxymethyl side arm have been conceived and their synthes...
Iminosugars are polyhydroxylated alkaloids, and can be generally defined as sugar mimetics in which ...
Azadisaccharides e.g. 399 (Figure 1) are known to be potent selective inhibitors of glycosidases and...
The biological activity of azasugars has largely been attributed to their ability to mimic the oxoca...
Highly regioselective 1,3-dipolar cycloadditions between d-arabinose-derived nitrones and d-mannitol...
Synthesis of some novel aminocyclopentitol analogues has been achieved through a functionally embell...
Glycosidase inhibitors have recently demonstrated promise in the fight against diabetes and possibly...
An efficient asymmetric synthesis of isofagomine, based on a precursor containing three differentiat...
Azasugars [e.g., 1-deoxy-aza-xylopyranose (1) Figure 1] are structural analogues of sugars [e.g., α-...
The syntheses of the polyhydroxylated piperidines deoxygalactonojirimycin 2, homogalactonojirimycins...
The main purpose of this work was the synthesis of polyhydroxylated pyrrolizidines and aza-C-disacch...
- A new expeditious preparation of homochiral (-)-1-azafagomine, and (+)-5-epi-1-azafagomine has bee...
A stereoselective synthesis of new isofagomine analogues has been achieved from a suitably functiona...
A new synthesis of deoxynojirimycin (DNJ) analogues (galacto- and altrose configuration) has been ac...
This comprehensive review deals with the synthesis of 1-azafagomine, analogs, and derivatives having...
New hydroxy azepanes with an additional hydroxymethyl side arm have been conceived and their synthes...
Iminosugars are polyhydroxylated alkaloids, and can be generally defined as sugar mimetics in which ...
Azadisaccharides e.g. 399 (Figure 1) are known to be potent selective inhibitors of glycosidases and...
The biological activity of azasugars has largely been attributed to their ability to mimic the oxoca...
Highly regioselective 1,3-dipolar cycloadditions between d-arabinose-derived nitrones and d-mannitol...
Synthesis of some novel aminocyclopentitol analogues has been achieved through a functionally embell...
Glycosidase inhibitors have recently demonstrated promise in the fight against diabetes and possibly...
An efficient asymmetric synthesis of isofagomine, based on a precursor containing three differentiat...
Azasugars [e.g., 1-deoxy-aza-xylopyranose (1) Figure 1] are structural analogues of sugars [e.g., α-...
The syntheses of the polyhydroxylated piperidines deoxygalactonojirimycin 2, homogalactonojirimycins...
The main purpose of this work was the synthesis of polyhydroxylated pyrrolizidines and aza-C-disacch...
- A new expeditious preparation of homochiral (-)-1-azafagomine, and (+)-5-epi-1-azafagomine has bee...
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