The RecA-like proteins constitute a group of DNA strand transfer proteins ubiquitous in eubacteria, eukarya, and archaea. However, the functional relationship among RecA proteins is poorly understood. For instance, Mycobacterium tuberculosis RecA is synthesized as a large precursor, which undergoes an unusual protein-splicing reaction to generate an active form. Whereas the precursor was inactive, the active form promoted DNA strand transfer less efficiently compared to EcRecA. Furthermore, gene disruption studies have indicated that the frequencies of allele exchange are relatively lower in Mycobacterium tuberculosis compared to Mycobacterium smegmatis. The mechanistic basis and the factors that contribute to differences in allele exchange...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
The RecA-like proteins constitute a group of DNA strand transfer proteins ubiquitous in eubacteria, ...
The RecA-like proteins constitute a group of DNA strand transfer proteins ubiquitous in eubacteria, ...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
To gain insights into inefficient allele exchange in mycobacteria, we compared homologous pairing an...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
To gain insights into inefficient allele exchange in mycobacteria, we compared homologous pairing an...
One of the fundamental questions concerning homologous recombination is how RecA or its homologues r...
One of the fundamental questions concerning homologous recombination is how RecA or its homologues r...
Mycobacterium leprae is closely related to Mycobacterium tuberculosis, yet causes a very different i...
Mycobacterium leprae is closely related to Mycobacterium tuberculosis, yet causes a very different i...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
The RecA-like proteins constitute a group of DNA strand transfer proteins ubiquitous in eubacteria, ...
The RecA-like proteins constitute a group of DNA strand transfer proteins ubiquitous in eubacteria, ...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
To gain insights into inefficient allele exchange in mycobacteria, we compared homologous pairing an...
In eubacteria, RecA proteins belong to a large superfamily of evolutionarily conserved, filament-for...
To gain insights into inefficient allele exchange in mycobacteria, we compared homologous pairing an...
One of the fundamental questions concerning homologous recombination is how RecA or its homologues r...
One of the fundamental questions concerning homologous recombination is how RecA or its homologues r...
Mycobacterium leprae is closely related to Mycobacterium tuberculosis, yet causes a very different i...
Mycobacterium leprae is closely related to Mycobacterium tuberculosis, yet causes a very different i...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...
DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabol...