N-Cinnamoyl-L-proline can be used as a template on which β-substituted phenylalanine and β-phenylisoserine residues can be synthesized leading to tripeptide derivatives as structural analogues of HIV protease inhibitors
New amino acids are reported in which component macrocycles are constrained to mimic tripeptides loc...
A γ-turn induced cyclisation of tripeptides 4 can be performed in a ring-closing metathesis rea...
Biologically active peptides and their receptors are involved in many of life's essential processes....
HIV-1 protease binds to its peptide/protein substrates in extended conformations. Therefore protease...
A new protocol is described for the stereocontrolled synthesis of pseudo-C2-symmetric core units of ...
New pseudopeptides possessing C2 symmetry and dihydroxyethylene core derived from (R,R)- tartaric ac...
498-506A cobalt-catalyzed combinatorial synthesis of various β-phenylisoserinederivatives is describ...
A new and stereoselective method to synthesize hydroxyethylamine and hydroxymethylamide peptide bond...
The synthesis of a novel and versatile (2S,5S)-2,5-bis-[(1,1'-dimethylethoxy)carbonylamino]-1,6-diph...
In the image: The design and synthesis of peptidomimetics that maintain the configuration of the tri...
C2 symmetric and non-symmetric pseudopeptide inhibitors of HIV-1 protease, containing a S,S,S,S-diam...
A central goal of modern biology is to develop a detailed, predictive understanding of the relations...
We describe the synthesis of a variety of lipophilic isosteres of nucleoside triphosphates as potent...
C2 symmetric and non-symmetric pseudopeptide inhibitors of HIV-1 protease, containing a S,S,S,S-diam...
Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AI...
New amino acids are reported in which component macrocycles are constrained to mimic tripeptides loc...
A γ-turn induced cyclisation of tripeptides 4 can be performed in a ring-closing metathesis rea...
Biologically active peptides and their receptors are involved in many of life's essential processes....
HIV-1 protease binds to its peptide/protein substrates in extended conformations. Therefore protease...
A new protocol is described for the stereocontrolled synthesis of pseudo-C2-symmetric core units of ...
New pseudopeptides possessing C2 symmetry and dihydroxyethylene core derived from (R,R)- tartaric ac...
498-506A cobalt-catalyzed combinatorial synthesis of various β-phenylisoserinederivatives is describ...
A new and stereoselective method to synthesize hydroxyethylamine and hydroxymethylamide peptide bond...
The synthesis of a novel and versatile (2S,5S)-2,5-bis-[(1,1'-dimethylethoxy)carbonylamino]-1,6-diph...
In the image: The design and synthesis of peptidomimetics that maintain the configuration of the tri...
C2 symmetric and non-symmetric pseudopeptide inhibitors of HIV-1 protease, containing a S,S,S,S-diam...
A central goal of modern biology is to develop a detailed, predictive understanding of the relations...
We describe the synthesis of a variety of lipophilic isosteres of nucleoside triphosphates as potent...
C2 symmetric and non-symmetric pseudopeptide inhibitors of HIV-1 protease, containing a S,S,S,S-diam...
Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AI...
New amino acids are reported in which component macrocycles are constrained to mimic tripeptides loc...
A γ-turn induced cyclisation of tripeptides 4 can be performed in a ring-closing metathesis rea...
Biologically active peptides and their receptors are involved in many of life's essential processes....