Layered double hydroxides containing chiral organic guests: synthesis, characterization and application for asymmetric C-C bond-forming reactions

We designed and developed two heterogeneous enantioselective catalysts, LDH-proline and LDH-BINOL, by incorporating chiral organic molecules viz., L-proline and S-BINOL, into layered double hydroxides (LDHs). These catalysts are characterized by IR, UV/vis and TGA analysis. These organo-LDHs have been successfully employed for various asymmetric C-C bond-forming transformations, and the products are obtained with good to excellent yields albeit low enantiomeric excess