IDENTIFICATION DRPs IN WRONG DRUG CATEGORY AND DRUG INTERACTION TO TYPE-2 DIABETES MELLITUS INPATIENTS IN GATOT SOEBROTO ARMY CENTRAL HOSPITAL JAKARTA

Drug Related Problems (DRPs) are unwanted incidence that happen to patients associated with drug therapy. Among the categories of DRPs are incorrect drug selection and dmg interactions, which are often found in common patients who have the disease, such as type 2 diabetes mellitus. This study aimed to determine the incidence of DRPs with category of incorrect dmg selection and dmg interactions in patients with type 2 diabetes mellitus in Gatot Subroto Army Central Hospital Jakarta. This research was conducted with non-experimental descriptive design and data acquisition retrospectively for medical record data. The patient’s criteria as subject in this study were inpatient in Gatot Subroto Army Central Hospital in Jakarta, diagnosed with type-2 diabetes mellitus. have no pregnancy during the study, receive diabetes mellitus medications, and have complete medical record data. The data were analyzed descriptively. The results showed there were 42 patients diagnosed with diabetes mellitus type 2 in which 50% of men and 50% of women, with aged 40-60 years 64.29% and > 61 years 35.71%. Single hypoglycemic drugs most widely used class of short-acting insulin as much as 83.3%. hypoglycemic dmg combination is the most widely used short-acting insulin + long-acting insulin as much as 54.76%. From 42 patients. 12 patients (28.57%) experienced DRPs with category of incorrect dmg selection including the used of unsafe drugs 19.05%. incorrect drugs 7.14%. and dmg combinations that are not necessary 2.38 %. On DRPs with category of dmg interactions, patients can receive more than one drug interactions. From 42 patients observed 112 dmg interactions, there were 47 (41.96%) cases were interaction between sullonylurea with other dmgs. cause increasing effect of sulfonylurea dmgs that pose an increased risk of hypoglycemic. 29 (69.05%) cases were interaction between sulfonylurea with other dmgs caused decreased effect sulfonylurea and 36 (32.14%) cases were interaction between metformin with other dmgs caused increasing the risk of hypoglycemic effect