Add to ORKGWe have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by targeting carbohydrate antigens. This type of immunization is associated with reduced survival after cecal ligation and puncture (CLP). In the present study, we investigated further this phenomenon by immunizing Lewis rats with three intraperitoneal injections, every other day, of hamster blood compared to saline-injected control animals. One day after the last injection, CLP was performed to produce a low-grade sepsis. Induction of xenoantibodies was associated with a reduction in animal survival after CLP relative to controls (45% vs. 90%, p<0.01). No bacterial blood load was observed after CLP in this model either with or without xenoantib...
INTRODUCTION: Systemic sepsis occurs in 20-50 % of patients admitted to non-cardiac intensive care u...
Sepsis is a disease syndrome covering many different aspects of the host immune system. Our understa...
0.01 vs. controls). In untreated control rats, xenoreactive antibody (IgM, IgG) levels decreased imm...
We have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by ...
<div><p>We have previously described that boosted natural xenoantibodies in rats cross-react to bact...
We have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by ...
The goal of this work was to induce clinical sepsis in rats in order to measure the following bioch...
The effect of extracorporeal blood purification on clinical outcomes in sepsis is assumed to be rela...
The effect of extracorporeal blood purification on clinical outcomes in sepsis is assumed to be rela...
<p>Groups of 6 Fischer 344 rats were vaccinated with LVS, LVS-R, HK-LVS, or PBS (naïve) for a total ...
<div><p>Rats with Metabolic Syndrome (MetaS) have a dysregulated immune response to the aseptic trau...
Most animal models of sepsis induced high mortality or early recovery and do not mimic the long-last...
Note:Lethality, weight loss and Tumor Necrosis Factor (TNF) production induced by lypopolysaccharide...
Sepsis is a serious medical condition characterized by dysregulated systemic inflammatory responses ...
The purpose of the present study was to better understand the events involved in the febrile respons...
INTRODUCTION: Systemic sepsis occurs in 20-50 % of patients admitted to non-cardiac intensive care u...
Sepsis is a disease syndrome covering many different aspects of the host immune system. Our understa...
0.01 vs. controls). In untreated control rats, xenoreactive antibody (IgM, IgG) levels decreased imm...
We have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by ...
<div><p>We have previously described that boosted natural xenoantibodies in rats cross-react to bact...
We have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by ...
The goal of this work was to induce clinical sepsis in rats in order to measure the following bioch...
The effect of extracorporeal blood purification on clinical outcomes in sepsis is assumed to be rela...
The effect of extracorporeal blood purification on clinical outcomes in sepsis is assumed to be rela...
<p>Groups of 6 Fischer 344 rats were vaccinated with LVS, LVS-R, HK-LVS, or PBS (naïve) for a total ...
<div><p>Rats with Metabolic Syndrome (MetaS) have a dysregulated immune response to the aseptic trau...
Most animal models of sepsis induced high mortality or early recovery and do not mimic the long-last...
Note:Lethality, weight loss and Tumor Necrosis Factor (TNF) production induced by lypopolysaccharide...
Sepsis is a serious medical condition characterized by dysregulated systemic inflammatory responses ...
The purpose of the present study was to better understand the events involved in the febrile respons...
INTRODUCTION: Systemic sepsis occurs in 20-50 % of patients admitted to non-cardiac intensive care u...
Sepsis is a disease syndrome covering many different aspects of the host immune system. Our understa...
0.01 vs. controls). In untreated control rats, xenoreactive antibody (IgM, IgG) levels decreased imm...