Add to ORKGA growing body of research shows that epigenetic mechanisms are critically involved in normal and pathological aging. The Senescence-Accelerated Mouse Prone 8 (SAMP8) can be considered a useful tool to better understand the dynamics of the global epigenetic landscape during the aging process since its phenotype is not fully explained by genetic factors. Here we investigated dysfunctional age-related transcriptional profiles and epigenetic programming enzymes in the hippocampus of 2- and 9-month-old SAMP8 female mice using the Senescent-Accelerated Resistant 1 (SAMR1) mouse strain as control. SAMP8 mice presented 1,062 genes dysregulated at 2 months of age, and 1,033 genes at 9 months, with 92 genes concurrently dysregulated at both ages com...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
Senescence-accelerated mouse prone 8 (SAMP8) is considered as a useful animal model for age-related ...
DoctorAging is often accompanied by cognitive decline, a critical public health issue in our rapidly...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
Harboring the behavioral and histopathological signatures of Alzheimer’s disease (AD), senescence ac...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
Senescence-accelerated mouse prone 8 (SAMP8) is considered as a useful animal model for age-related ...
DoctorAging is often accompanied by cognitive decline, a critical public health issue in our rapidly...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
A growing body of research shows that epigenetic mechanisms are critically involved in normal and pa...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
Harboring the behavioral and histopathological signatures of Alzheimer’s disease (AD), senescence ac...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's ...
Senescence-accelerated mouse prone 8 (SAMP8) is considered as a useful animal model for age-related ...
DoctorAging is often accompanied by cognitive decline, a critical public health issue in our rapidly...