Add to ORKGFatty acids are key components in the structural diversity of lipids and play a strategic role in the functional properties of lipids which determine the structural and functional integrity of neural cell membranes, the generation of lipid signaling mediators, and the chemical reactivity of acyl chains. The present study analyzes the profile of lipid fatty acid composition of membranes of human frontal cortex area 8 in individuals ranging from 40 to 90 years old. Different components involved in polyunsaturated fatty acid biosynthesis pathways, as well as adaptive defense mechanisms involved in the lipid-mediated modulation of inflammation, are also assessed. Our results show that the lipid profile in human frontal cortex is basically prese...
As the brain ages, cognitive and motor performance decline. This decline is thought to be largely du...
Immune function changes across the life course; the fetal immune system is characterised by toleranc...
In addition to a gradual loss of neurons in various brain regions, major biochemical changes in the ...
Fatty acids are key components in the structural diversity of lipids and play a strategic role in th...
Membrane lipid composition is altered in the brain during the pathogenesis of several age-related ne...
Lipid rafts are highly dynamic membrane domains featured by distinctive biochemical composition and ...
Fatty acids are key components in the structural diversity of lipids and play a strategic role in th...
The human brain is a target of the aging process like other cell systems of the human body. Specific...
Lipids constitute a significant group of biological metabolites and the building blocks of all cell ...
The world’s population is rapidly ageing, and with that has come a corresponding increase in the num...
Lipids are essential to brain functions, yet they remain largely unexplored. Here we investigated th...
Human prefrontal cortex (PFC) is a recently evolutionary emerged brain region involved in cognitive ...
Differences in lipid metabolism associate with age-related disease development and lifespan. Inflamm...
Lipids are closely associated with brain structure and function. However, the potential changes in t...
One of the biggest risk factors for developing Alzheimer\u27s disease is advanced age. Despite sever...
As the brain ages, cognitive and motor performance decline. This decline is thought to be largely du...
Immune function changes across the life course; the fetal immune system is characterised by toleranc...
In addition to a gradual loss of neurons in various brain regions, major biochemical changes in the ...
Fatty acids are key components in the structural diversity of lipids and play a strategic role in th...
Membrane lipid composition is altered in the brain during the pathogenesis of several age-related ne...
Lipid rafts are highly dynamic membrane domains featured by distinctive biochemical composition and ...
Fatty acids are key components in the structural diversity of lipids and play a strategic role in th...
The human brain is a target of the aging process like other cell systems of the human body. Specific...
Lipids constitute a significant group of biological metabolites and the building blocks of all cell ...
The world’s population is rapidly ageing, and with that has come a corresponding increase in the num...
Lipids are essential to brain functions, yet they remain largely unexplored. Here we investigated th...
Human prefrontal cortex (PFC) is a recently evolutionary emerged brain region involved in cognitive ...
Differences in lipid metabolism associate with age-related disease development and lifespan. Inflamm...
Lipids are closely associated with brain structure and function. However, the potential changes in t...
One of the biggest risk factors for developing Alzheimer\u27s disease is advanced age. Despite sever...
As the brain ages, cognitive and motor performance decline. This decline is thought to be largely du...
Immune function changes across the life course; the fetal immune system is characterised by toleranc...
In addition to a gradual loss of neurons in various brain regions, major biochemical changes in the ...