Add to ORKGBACKGROUND AND AIM: Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the development of diagnostic, prognostic and predictive biomarkers in human cancer, including colorectal cancer (CRC). The aim of this study was to perform a systematic and comprehensive analysis of a panel of CRC-specific genes as potential diagnostic, prognostic and predictive biomarkers in a large, population-based CRC cohort. PATIENTS AND METHODS: Methylation status of the SEPT9, TWIST1, IGFBP3, GAS7, ALX4 and miR137 genes was studied by quantitative bisulfite pyrosequencing in a population-based cohort of 425 CRC patients. RESULTS: Methylation levels of all genes analyzed were significantly higher in tumor tissues compared to ...
Background: Patients with ulcerative colitis and Crohn's colonic disease are at increased risk of de...
<div><p>Microarray analysis of promoter hypermethylation provides insight into the role and extent o...
Colorectal carcinoma (CRC) is one of the most common cancers, and is associated with a poor clinical...
Background and Aim: Aberrant hypermethylation of cancer-related genes has emerged as a promising str...
Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the develo...
<div><p>Background and Aim</p><p>Aberrant hypermethylation of cancer-related genes has emerged as a ...
BACKGROUND AND AIM: Aberrant hypermethylation of cancer-related genes has emerged as a promising str...
Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the develo...
Insulin-like growth factor binding protein 3 (IGFBP3), which is induced by wild-type p53, regulates ...
AbstractInsulin-like growth factor binding protein 3 (IGFBP3), which is induced by wild-type p53, re...
Background: The development of colorectal cancer (CRC) is accompanied by extensive epigenetic change...
Abstract Background Colorectal cancer (CRC) is one of the most incident cancers, associated with sig...
[[abstract]]Background: DNA methylationis a potential tumor marker for several cancers, including co...
BACKGROUND: IGFBP-3 is a multifunctional protein that inhibits growth and induces apoptosis of cance...
[[abstract]]Background: DNA methylationis a potential tumor marker for several cancers, including co...
Background: Patients with ulcerative colitis and Crohn's colonic disease are at increased risk of de...
<div><p>Microarray analysis of promoter hypermethylation provides insight into the role and extent o...
Colorectal carcinoma (CRC) is one of the most common cancers, and is associated with a poor clinical...
Background and Aim: Aberrant hypermethylation of cancer-related genes has emerged as a promising str...
Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the develo...
<div><p>Background and Aim</p><p>Aberrant hypermethylation of cancer-related genes has emerged as a ...
BACKGROUND AND AIM: Aberrant hypermethylation of cancer-related genes has emerged as a promising str...
Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the develo...
Insulin-like growth factor binding protein 3 (IGFBP3), which is induced by wild-type p53, regulates ...
AbstractInsulin-like growth factor binding protein 3 (IGFBP3), which is induced by wild-type p53, re...
Background: The development of colorectal cancer (CRC) is accompanied by extensive epigenetic change...
Abstract Background Colorectal cancer (CRC) is one of the most incident cancers, associated with sig...
[[abstract]]Background: DNA methylationis a potential tumor marker for several cancers, including co...
BACKGROUND: IGFBP-3 is a multifunctional protein that inhibits growth and induces apoptosis of cance...
[[abstract]]Background: DNA methylationis a potential tumor marker for several cancers, including co...
Background: Patients with ulcerative colitis and Crohn's colonic disease are at increased risk of de...
<div><p>Microarray analysis of promoter hypermethylation provides insight into the role and extent o...
Colorectal carcinoma (CRC) is one of the most common cancers, and is associated with a poor clinical...