Add to ORKGWe report a methodology for the catalytic asymmetric cross-coupling of two C(sp3)–H bonds employing visible light as an economical and environmentally benign source of energy. Photoredox catalysis is used for the oxidation of a diarylmethane to the corresponding cation, which is then trapped by an enamine intermediate generated in situ from an aldehyde reactant and a secondary amine organocatalyst. Notably, this mild method is an ideal synthetic approach from the green chemistry point of view. It does not require preinstallation of functional groups, thereby constituting an atom economical, efficient transformation, and it allows the formation of a C–C bond with simultaneous installation of one or two new stereocenters in a highly enantio- ...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...
This study reports the catalytic deracemization of ketones bearing stereocenters in the alpha-positi...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...
The direct, asymmetric α-amination of aldehydes has been accomplished via a combination of photoredo...
Chemical processes combining visible-light-activated redox catalysis with asymmetric catalysis are r...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
A highly efficient catalytic asymmetric alkyny\ation of prochiral CH2 groups in tetrahydroisoquinoli...
In Chapter 1, alkyl oxalates are described as new bench-stable alcohol activating groups for radical...
In the modern era of chemistry, photoredox catalysis has proven its usefulness in many synthetic app...
In this study, we combined photo-organo redox catalysis and biocatalysis to achieve asymmetric C–H b...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
In this study, we combined photo-organo redox catalysis and biocatalysis to achieve asymmetric C–H b...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...
This study reports the catalytic deracemization of ketones bearing stereocenters in the alpha-positi...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...
The direct, asymmetric α-amination of aldehydes has been accomplished via a combination of photoredo...
Chemical processes combining visible-light-activated redox catalysis with asymmetric catalysis are r...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mo...
A highly efficient catalytic asymmetric alkyny\ation of prochiral CH2 groups in tetrahydroisoquinoli...
In Chapter 1, alkyl oxalates are described as new bench-stable alcohol activating groups for radical...
In the modern era of chemistry, photoredox catalysis has proven its usefulness in many synthetic app...
In this study, we combined photo-organo redox catalysis and biocatalysis to achieve asymmetric C–H b...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
In this study, we combined photo-organo redox catalysis and biocatalysis to achieve asymmetric C–H b...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...
This study reports the catalytic deracemization of ketones bearing stereocenters in the alpha-positi...
Herein we describe our efforts to elucidate the key mechanistic aspects of the previously reported e...