Add to ORKGLiNH2BH3-promoted reductive opening of 8-substituted phenylglycinol-derived oxazolopiperidone lactams leads to enantiopure 4-substituted-5-aminopentanols, which are used as starting building blocks in the synthesis of the Haliclona alkaloids haliclorensin C, haliclorensin, and halitulin (formal). The starting lactams are easily accessible by a cyclocondensation reaction of (R)-phenylglycinol with racemic γ-subtituted δ-oxoesters, in a process that involves a dynamic kinetic resolution
International audienceVarious chiral α,β-unsaturated γ-lactams 1 were prepared in high yield and in ...
This Focus Review highlights recent developments in the organocatalytic enantioselective synthesis o...
The enantioselective synthesis of a N-benzyl substituted beta-lactam 5a, a precursor for carbapenem ...
LiNH<sub>2</sub>BH<sub>3</sub>-promoted reductive opening of 8-substituted phenylglycinol-derived ox...
LiNH2BH3-promoted reductive opening of 8-substituted phenylglycinol-derived oxazolopiperidone lactam...
[eng] 1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-c...
The enantioselective synthesis (3.7% overall yield in nine steps from 2) and biological screening of...
A variety of (R)-phenylglycinol-derived oxazolopiperidone lactams 1-14 were converted to linear-chai...
The stereocontrolled dialkylation at the carbonyl α-position of simple phenylglycinol-derived oxazol...
In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones,...
This account reports on the use of (R)- or (S)-phenylglycinol- and (S)-tryptophanol-derived oxazolop...
Cyclocondensation reactions between a variety of 2‐acyl‐3‐indoleacetic acid derivatives and (R )‐phe...
Starting from tricyclic lactam 2 , which is easily accessible by cyclocondensation of δ‐oxoester 1 w...
The synthesis of the Lycopodium alkaloids, (-)-cermizine B, (+)-serratezomine E, and (+)-luciduline ...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
International audienceVarious chiral α,β-unsaturated γ-lactams 1 were prepared in high yield and in ...
This Focus Review highlights recent developments in the organocatalytic enantioselective synthesis o...
The enantioselective synthesis of a N-benzyl substituted beta-lactam 5a, a precursor for carbapenem ...
LiNH<sub>2</sub>BH<sub>3</sub>-promoted reductive opening of 8-substituted phenylglycinol-derived ox...
LiNH2BH3-promoted reductive opening of 8-substituted phenylglycinol-derived oxazolopiperidone lactam...
[eng] 1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-c...
The enantioselective synthesis (3.7% overall yield in nine steps from 2) and biological screening of...
A variety of (R)-phenylglycinol-derived oxazolopiperidone lactams 1-14 were converted to linear-chai...
The stereocontrolled dialkylation at the carbonyl α-position of simple phenylglycinol-derived oxazol...
In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones,...
This account reports on the use of (R)- or (S)-phenylglycinol- and (S)-tryptophanol-derived oxazolop...
Cyclocondensation reactions between a variety of 2‐acyl‐3‐indoleacetic acid derivatives and (R )‐phe...
Starting from tricyclic lactam 2 , which is easily accessible by cyclocondensation of δ‐oxoester 1 w...
The synthesis of the Lycopodium alkaloids, (-)-cermizine B, (+)-serratezomine E, and (+)-luciduline ...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
International audienceVarious chiral α,β-unsaturated γ-lactams 1 were prepared in high yield and in ...
This Focus Review highlights recent developments in the organocatalytic enantioselective synthesis o...
The enantioselective synthesis of a N-benzyl substituted beta-lactam 5a, a precursor for carbapenem ...