Возбудители остеомиелита длинных костей и их резистентность

Objective: to study the dynamics of changes in the structure of osteomyelitis agents of the long bones and their sensitivity to germicide depending on the surgical treatment strategy.Materials and methods. There were studied 1083 patterns of clinical material from 384 patients with different forms of the osteomyelitis of the long bones that were treated in a period from 2013 to 2015 in the Department of Wound and Wound Infections of A.V. Vishnevsky Institute of Surgery. The comparison group consisted of microbiological studies results of 115 similar patients who were on treatment for osteomyelitis in the same Department in 2010.Results. The main osteomyelitis agents of the long bones both in the main and in the comparison group are representatives of the gram-positive coccal flora – S. aureus, S. epidermidis and in a less degree E. faecalis. Among gram-negative bacterium P. aeruginosa keeps the leading position. However, in the main group of patients it is noticed a significant reduction of leading pathogens resistance, and a detection of hospital re- and superinfection flora breakdown. Clinically, it is expressed by the fact that there were developed a surgical strategy of osteomyelitis of the long bones treatment of different etiology and localization in the Department of Wound and Wound Infections, which allow improving the results of treatment for such patients by reducing their length of stay in hospital and the possibility to avoid the infection of wounds by hospital strains of microorganisms