Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid.
- Hirst, Robert A.
- Jackson, Claire L.
- Coles, Janice L.
- Williams, Gwyneth
- Rutman, Andrew
- Goggin, Patricia M.
- Adam, Elizabeth C.
- Page, Anthony
- Evans, Hazel J.
- Lackie, Peter M.
- O'Callaghan, Christopher
- Lucas, Jane S
Publication date
February 2014
DOI Publisher
Public Library of Science (PLoS)Abstract
The change to ciliary phenotype in PCD samples following cell culture does not affect the diagnosis, and in certain cases can assist the ability to identify PCD cilia
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