SOX2 expression is linked to the undifferentiated state of stem cells in mammalian neurogenic niches. While its expression has been reported in the adult human subventricular zone (SVZ), to date it has not been detected in adult human white matter. Here we describe a population of SOX2+ cells from the white matter of the adult human temporal lobe, which proliferate and express glial markers in vitro
The embryonic and adult central nervous systems (CNS) harbor heterogeneous populations of proliferat...
AbstractThe transcription factor, Sox1 has been implicated in the maintenance of neural progenitor c...
Glial cells can be in vivo reprogrammed into functional neurons in the adult CNS; however, the proce...
We identified a rare undifferentiated cell population that is intermingled with the Bergmann glia of...
<div><p>Objectives</p><p>A number of neurodegenerative diseases progress with a loss of myelin, whic...
SummaryTo characterize the properties of adult neural stem cells (NSCs), we generated and analyzed S...
Objectives: A number of neurodegenerative diseases progress with a loss of myelin, which makes them ...
Adult neurogenesis is well-described in the subventricular and subgranular zones of the mammalian br...
expansion, and further implantation. Cells expressing A2B5 or PDGFRA/CNP have been isolated within ...
The HMG-Box transcription factor SOX2 is expressed in neural progenitor populations throughout the d...
Neural stem cells (NSCs) have been found to reside in defined areas of the vertebrate brain, where t...
SOX2 is one of the key transcription factors involved in maintenance of neural progenitor identity. ...
In many species, the Sox2 transcription factor is a marker of the nervous system from the beginning ...
Sox2 is a key transcription factor that maintains the proliferation of neuroglial stem cells and in...
SummarySOX2 is involved in several cell and developmental processes, including maintenance of embryo...
The embryonic and adult central nervous systems (CNS) harbor heterogeneous populations of proliferat...
AbstractThe transcription factor, Sox1 has been implicated in the maintenance of neural progenitor c...
Glial cells can be in vivo reprogrammed into functional neurons in the adult CNS; however, the proce...
We identified a rare undifferentiated cell population that is intermingled with the Bergmann glia of...
<div><p>Objectives</p><p>A number of neurodegenerative diseases progress with a loss of myelin, whic...
SummaryTo characterize the properties of adult neural stem cells (NSCs), we generated and analyzed S...
Objectives: A number of neurodegenerative diseases progress with a loss of myelin, which makes them ...
Adult neurogenesis is well-described in the subventricular and subgranular zones of the mammalian br...
expansion, and further implantation. Cells expressing A2B5 or PDGFRA/CNP have been isolated within ...
The HMG-Box transcription factor SOX2 is expressed in neural progenitor populations throughout the d...
Neural stem cells (NSCs) have been found to reside in defined areas of the vertebrate brain, where t...
SOX2 is one of the key transcription factors involved in maintenance of neural progenitor identity. ...
In many species, the Sox2 transcription factor is a marker of the nervous system from the beginning ...
Sox2 is a key transcription factor that maintains the proliferation of neuroglial stem cells and in...
SummarySOX2 is involved in several cell and developmental processes, including maintenance of embryo...
The embryonic and adult central nervous systems (CNS) harbor heterogeneous populations of proliferat...
AbstractThe transcription factor, Sox1 has been implicated in the maintenance of neural progenitor c...
Glial cells can be in vivo reprogrammed into functional neurons in the adult CNS; however, the proce...