Many new lipophilic α-aminophosphonates including macrocylic (on calix[4]arene platform) and chiral ones were synthesized by the Kabachnik-Fields reaction. Some of them were examined as carriers for membrane transport of biorelevant species such as hydroxy, amino acids, and amino alcohols. Transport measurements showed that these compounds exhibited remarkable efficiency and selectivity of the transport of very hydrophilic substances across lipophilic membranes. The structures of α-amino-phosphonate-substrate complexes were investigated by spectral and theoretical methods
Some novel aminophosphoryl compounds were synthesized by the Kabachnik-Fields reaction. Their membra...
Selective transmembrane carriers for a-hydroxy acids, acyclic a-amino phosphonates and calix[4]arene...
A new type of macrocyclic receptor able to bind organic substrates containing carboxy and carboxylat...
Many new lipophilic α-aminophosphonates including macrocylic (on calix[4]arene platform) and chiral ...
The novel lipophilic α-aminophosphonates were synthesized by the Kabachnik-Fields reaction. These co...
A series of calix[4]arene based α-aminophosphonates were synthesized by the Kabachnik-Fields reactio...
New α-amino phosphonates containing different alkyl and aryl substituents at the α-carbon atom were ...
New lipophilic α-aminophosphonates containing cyclic or acyclic alkyl substituents at the carbon ato...
A series of aminophosphonates was synthesized, and their ability to carry alanine, a model hydrophil...
Some novel aminophosphoryl compounds were synthesized by the Kabachnik-Fields reaction. Their membra...
Selective transmembrane carriers for a-hydroxy acids, acyclic a-amino phosphonates and calix[4]arene...
A new type of macrocyclic receptor able to bind organic substrates containing carboxy and carboxylat...
Many new lipophilic α-aminophosphonates including macrocylic (on calix[4]arene platform) and chiral ...
The novel lipophilic α-aminophosphonates were synthesized by the Kabachnik-Fields reaction. These co...
A series of calix[4]arene based α-aminophosphonates were synthesized by the Kabachnik-Fields reactio...
New α-amino phosphonates containing different alkyl and aryl substituents at the α-carbon atom were ...
New lipophilic α-aminophosphonates containing cyclic or acyclic alkyl substituents at the carbon ato...
A series of aminophosphonates was synthesized, and their ability to carry alanine, a model hydrophil...
Some novel aminophosphoryl compounds were synthesized by the Kabachnik-Fields reaction. Their membra...
Selective transmembrane carriers for a-hydroxy acids, acyclic a-amino phosphonates and calix[4]arene...
A new type of macrocyclic receptor able to bind organic substrates containing carboxy and carboxylat...