Mean platelet volume: A controversial marker of disease activity in Crohn’s disease
- Liu, Song
- Ren, Jianan
- Han, Gang
- Wang, Gefei
- Gu, Guosheng
- Xia, Qiuyuan
- Li, Jieshou
DOIAbstract
Background: We investigated and compared the capacity of mean platelet volume (MPV) and other inflammatory markers in detecting Crohn’s disease (CD) activity and differentiating CD patients from healthy controls. Methods: MPV, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and white blood cells were measured in 61 CD patients and 50 healthy subjects. Disease activity was assessed by the Crohn’s Disease Activity Index. Results: A significant decrease in MPV was noted in patients with CD compared with healthy controls (P <0.0001), but statistical difference was not found between active and inactive CD groups. In CD, no significant correlation was found between MPV and other inflammatory markers. The overall accuracy of MPV (cu...
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