Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs. See research article: http://www.biomedcentral.com/1752-0509/4/58
Although cancer has historically been viewed as a disorder of proliferation, recent evidence has sug...
Despite decades of intensive scientific and medical efforts to develop efficient and effective treat...
Cellular metabolism influences life and death decisions. An emerging theme in cancer biology is that...
A defining hallmark of cancer is uncontrolled cell proliferation. This is initiated once cells have ...
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic a...
Cancer cells must rewire cellular metabolism to satisfy the demands of growth and proliferation. Alt...
<p>It has been long known that many types of cancers have high metabolic requirements and use reprog...
Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth...
It has been known for decades that cancer cells exhibit enhanced rates of Glucose uptake and glycoly...
The essential hallmarks of cancer are intertwined with an altered cancer cell-intrinsic metabolism, ...
AbstractCancer is a disease characterized by unrestrained cellular proliferation. In order to sustai...
Tumor cells alter their metabolism to maintain unregulated cellular proliferation and survival, but ...
Cancer cells exhibit profound metabolic alterations, allowing them to fulfill the metabolic needs th...
Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth...
Unrestricted cancer growth requires permanent supply of glucose that can be obtained from cancer-med...
Although cancer has historically been viewed as a disorder of proliferation, recent evidence has sug...
Despite decades of intensive scientific and medical efforts to develop efficient and effective treat...
Cellular metabolism influences life and death decisions. An emerging theme in cancer biology is that...
A defining hallmark of cancer is uncontrolled cell proliferation. This is initiated once cells have ...
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic a...
Cancer cells must rewire cellular metabolism to satisfy the demands of growth and proliferation. Alt...
<p>It has been long known that many types of cancers have high metabolic requirements and use reprog...
Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth...
It has been known for decades that cancer cells exhibit enhanced rates of Glucose uptake and glycoly...
The essential hallmarks of cancer are intertwined with an altered cancer cell-intrinsic metabolism, ...
AbstractCancer is a disease characterized by unrestrained cellular proliferation. In order to sustai...
Tumor cells alter their metabolism to maintain unregulated cellular proliferation and survival, but ...
Cancer cells exhibit profound metabolic alterations, allowing them to fulfill the metabolic needs th...
Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth...
Unrestricted cancer growth requires permanent supply of glucose that can be obtained from cancer-med...
Although cancer has historically been viewed as a disorder of proliferation, recent evidence has sug...
Despite decades of intensive scientific and medical efforts to develop efficient and effective treat...
Cellular metabolism influences life and death decisions. An emerging theme in cancer biology is that...