RBFOX2 and alternative splicing in B-cell lymphoma
- Quentmeier, Hilmar
- Pommerenke, Claudia
- Bernhart, Stephan H.
- Dirks, Wilhelm G.
- Hauer, Vivien
- Hoffmann, Steve
- Nagel, Stefan
- Siebert, Reiner
- Uphoff, Cord C.
- Zaborski, Margarete
- Drexler, Hans G.
- ICGC MMML-Seq Consortium
Publication date
January 2018
DOI Publisher
Springer Science and Business Media LLCAbstract
RBFOX2 is a master regulator of alternative splicing1. This RNA-binding protein (RBP) is expressed in the brain2, muscle3, and embryonic stem cells4. RBFOX2 is required not only for the proper splicing of target RNAs, but also for cerebellar development2, myogenesis3, and for survival of human embryonic stem cells4
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