[[alternative]]The illness Experience and Grief with Disease Progression after Breast Cancer Clinical Trial

[[abstract]]研究目的：探討乳癌臨床試驗個案疾病惡化之生病經驗及悲傷經驗。文獻：醫學科技沒有人體試驗就不會進步，美國進行中的癌症藥物研當中乳癌占了7％，而乳癌在女性癌症發生率排名順位第一，並文獻探討了解目前並沒有對於臨床試驗個案病情惡化之相關研究。研究方法：本研究透過深度訪談訪談5位受訪者，採半結構訪談，分析資料分為生病經驗、悲傷經驗二部分，將受訪資料經Atlas.ti 8學生版協助分析，依出現次數多寡分類，使用「類別－內容」逐步呈現內容。研究內容：生病經驗依照Kleinman (1988/ 1995)提出的生病經驗概念及內涵，分成乳癌治療、臨床試驗、症狀、文化意涵、生活世界的改變、支持系統、解釋與情緒進行分類。悲傷經驗依照Stroebe 和Schut(1999)提出的雙軌擺盪模式，分成悲傷、調適二者進行分類。研究結果：受訪者參與臨床試驗後依然出現病情惡化，其生病經驗之解釋因生活脈絡、臨床試驗設計等多元因素影響。悲傷經驗部分，乳癌臨床試驗個案的悲傷與生病意義纏繞，生病意義與情緒騷動相連並需在受訪者的脈絡下才能被理解。本研究針對研究結果提出相關討論與建議。[[abstract]]Research purposes: To explore the illness experience and grief with diseasepro-gression after breast cancer clinical trial. Literature: In the cancer therapy trials in the United States, breast cancer accounts for 7%. The report of cancer incidence rate in Taiwan breast cancer has the highest incidence. There was no study for breast cancer subject disease progression in clinical trial. Method: This research use depth interview. Interview 5 patients. The textual contents will analysis in accordance with Lieblich’s ‘category-content” analysis’ method by Atlas.ti 8 student version. Data is divided into two parts: illness experience and sad experience, presentation based on the number of occurrences. Research content: According to the concept of illness experience (Kleinman ,1988),the text divided into seven themes: breast cancer treatment, clinical trials, symptoms, psychocultural, changes in lifestyle, support systems, explanations and emotional. According to the two-track mode of bereavement proposed by Stroebe and Schut (1999), the text divided into two themes :grief, adapted. Results: The explain of illness experience of disease progress after breast cancer clinical trail is influenced by multiple factors such as life context and clinical trial design. The grief experience of disease progress after breast cancer clinical trial is entangled with meaning