Актуальные подходы к терапии вульвовагинитов с учетом антибиотикорезистентности инфекционных агентов

Aim of research: the study of qualitative composition and parameters of sensitivity/resistance to antibiotics of the different groups of biota of the low parts of genital tract in patients with nonspecific vulvovaginites.Methods of research: 242 women 18-47 years old underwent clinical-laboratory examination on the base of clinic and department of sexually transmitted infections SI “Institute of dermatology and venereology, NAMS of Ukraine”. They were divided in two groups: 1st group – 205 (84,7 %) patients with clinical and laboratory signs of vulvovaginitis; 2th group (control one) -– 37 (15,3 %) clinically healthy women. All patients, included in the research, underwent the complex of laboratory examinations according to the regulative documents of HM of Ukraine.Results of research: The composition of vaginal microbiocenosis in patients with vulgovaginites, caused by conventionally pathogenic microorganisms was characterized with the prevalence of aerobic representatives of Enterobacteriaceae and Staphylococcaceae families that formed association both between themselves and with representatives of the other taxonomic groups. The therapy of vulvovaginites, caused by aerobic conventionally pathogenic microorganisms, must be realized individually, taking into account the results of determination of sensitivity of the aerobic microflora. At impossibility of cultural study with determination of sensitivity of separated microorganisms to antibacterial remedies, the preparations of choice in the treatment of vulvovaginites, caused with conventionally pathogenic microorganisms can be quinolones, lincosamides, nitrofurans and ceftriaxone that the higher sensitivity of conventionally pathogenic microorganisms was observed toЦель исследования: изучение качественного состава и показателей чувствительности к антибиотикам разных групп биоты влагалища у пациенток с неспецифическими вульвовагинитами. Состав вагинального микробиоценоза характеризовался преобладанием представителей семейств Enterobacteriaceae и Staphylococcaceae. Лечение неспецифических вульвовагинитов должно проводиться индивидуально с учетов данных определения чувствительности выделенных возбудителей к антибиотикам различных груп