Signs and symptoms of acromegaly at diagnosis: the physician's and the patient's perspectives in the ACRO-POLIS study
- Caron, Philippe
- Brue, Thierry
- Raverot, Gerald
- Tabarin, Antoine
- Cailleux, Anne
- Delemer, Brigitte
- Renoult, Peggy Pierre
- Houchard, Aude
- Elaraki, Fatine
- Chanson, Philippe
DOIAbstract
International audienceAcromegaly is characterized by a broad range of manifestations. Early diagnosis is key to treatment success, but is often delayed as symptomatology overlaps with common disorders. We investigated sign-and-symptom associations, demographics, and clinical characteristics at acromegaly diagnosis.MethodsObservational, cross-sectional, multicenter non-interventional study conducted at 25 hospital departments in France that treat acromegaly (ClinicalTrials.gov: NCT02012127). Adults diagnosed with acromegaly<5 years were enrolled. Demographic and clinical data were obtained from medical reports and patient questionnaires. Sign-and-symptom associations were assessed by multiple correspondence analysis (MCA).ResultsOverall, 472...
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