International audienceMaternal malaria is associated with the sequestration, in the placenta, of Plasmodium falciparum-infected erythrocytes onto chondroitin sulfate A (CSA), via the duffy binding-like (DBL)-gamma3 domain of the P. falciparum erythrocyte membrane protein 1 (PfEMP1(CSA)) (DBL-gamma3(CSA)). The production of antibodies against CSA-binding infected erythrocytes (IEs(CSA)) is correlated with resistance to maternal malaria in multiparous women. We produced recombinant DBL-gamma3(CSA) (rDBL-gamma3(CSA)) in insect cells, corresponding to 2 variant DBL-gamma3(CSA) subtypes that mediate binding to CSA in laboratory lines and placental isolates. Both recombinant cysteine-rich DBL-gamma3(CSA) domains blocked IEs(CSA) binding to CSA. I...
The high molecular weight, multidomain VAR2CSA protein mediating adhesion of Plasmodium falciparum-i...
Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and ...
Acquired protection from Plasmodium falciparum placental malaria, a major cause of maternal, fetal, ...
Maternal malaria is associated with the sequestration, in the placenta, of Plasmodium falciparum–inf...
Placental malaria (PM) is characterized by infected erythrocytes (IEs) that selectively bind to chon...
International audienceLes parasites de Plasmodium falciparum expriment des molécules d'adhésion vari...
Abstract Background Pregnancy associated malaria is a severe clinical syndrome associated with seque...
International audienceProtection against maternal malaria has been associated with the acquisition o...
Abstract Background Malaria caused by Plasmodium falciparum can result in several different syndrome...
<div><p>Malaria during pregnancy in <em>Plasmodium falciparum</em> endemic regions is a major cause ...
BACKGROUND: In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an important co...
Plasmodium falciparum malaria remains one of the world's leading causes of human suffering and pover...
AbstractPlasmodium falciparum malaria remains one of the world's leading causes of human suffering a...
The Duffy binding-like (DBL) domains are common adhesion modules present in Plasmodium falciparum er...
AbstractPlacental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal and ...
The high molecular weight, multidomain VAR2CSA protein mediating adhesion of Plasmodium falciparum-i...
Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and ...
Acquired protection from Plasmodium falciparum placental malaria, a major cause of maternal, fetal, ...
Maternal malaria is associated with the sequestration, in the placenta, of Plasmodium falciparum–inf...
Placental malaria (PM) is characterized by infected erythrocytes (IEs) that selectively bind to chon...
International audienceLes parasites de Plasmodium falciparum expriment des molécules d'adhésion vari...
Abstract Background Pregnancy associated malaria is a severe clinical syndrome associated with seque...
International audienceProtection against maternal malaria has been associated with the acquisition o...
Abstract Background Malaria caused by Plasmodium falciparum can result in several different syndrome...
<div><p>Malaria during pregnancy in <em>Plasmodium falciparum</em> endemic regions is a major cause ...
BACKGROUND: In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an important co...
Plasmodium falciparum malaria remains one of the world's leading causes of human suffering and pover...
AbstractPlasmodium falciparum malaria remains one of the world's leading causes of human suffering a...
The Duffy binding-like (DBL) domains are common adhesion modules present in Plasmodium falciparum er...
AbstractPlacental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal and ...
The high molecular weight, multidomain VAR2CSA protein mediating adhesion of Plasmodium falciparum-i...
Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and ...
Acquired protection from Plasmodium falciparum placental malaria, a major cause of maternal, fetal, ...