Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study
- Oddone F.
- Tanga L.
- Kothy P.
- Hollo G.
- Faschinger C.
- Chen E.
- Hollo G.
- Nemeth G.
- Bator G.
- Tsorbatzoglou A.
- Acs T.
- Ferencz M.
- Sohajda Z.
- Toth J.
- Volner V.
- Vogt G.
- Biro Z.
- Facsko A.
- Nemes J.
- Berta A.
- Elek I.
- Ng E.
- Oddone F.
- Rossi G.
- Rossetti L.
- Vetrugno M.
- Iester M.
- Marchini G.
- Scorcia V.
- Staurenghi G.
- Cagini C.
- Salgarello T.
- Bettin P.
- Figus M.
- Scuderi G. L.
- De Cilla S.
- Grundmane I.
- Linavska N.
- Volksone L.
- Laganovska G.
- Baumane K.
- Lemij H.
- Gundersen K. G.
- Zimina M.
- Erichev V.
- Karlova E.
- Zakharova E.
- Panova I.
- Malyugin B.
- Aguirrec I. R.
- Lopez-Lopez F.
- Valladares A. M.
- del Castillo J. B.
- Gimenez R.
- Vallejo M. P.
- Medina J. G.
- Lopez A. A.
- Torregrosa S.
- Loscos J.
- Kolko M.
- Ansari E.
- Broadway D.
- Claridge K.
- Ruben S.
- Kirwan J.
- Nita A.
- Smith M.
- Moosavi A.
- King A. J. W.
- Kinsella M.
DOIAbstract
Introduction: A non-interventional, multicenter, European, prospective evaluation of the effectiveness, tolerability, and safety of a topical preservative-free tafluprost (0.0015%) and timolol (0.5%) fixed-dose combination (PF tafluprost/timolol FC) in adults with open-angle glaucoma (OAG) and ocular hypertension (OHT) demonstrating insufficient response to topical beta-receptor blockers or prostaglandin analogue (PGA) monotherapy. Methods: Mean intraocular pressure (IOP) change from baseline was measured at study visits following a switch to PF tafluprost/timolol FC. Primary endpoint was absolute mean IOP change at month 6. Change from baseline concerning ocular signs and symptoms was also explored. Results: Analyses included 577 pati...
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