Quantitative determination of phenolics compounds in Origanum vulgare extract by high-performance liquid chromatography coupled with tandem mass spectrometric detection

Phenolic compounds in 80% MeOH extract of oregano (Origanum vulgare L.) were analysed by reversed phase HPLC, follewed by tandem mass spectrometric detection. For the first time thirty nine phenolics, corresponding to flavonoids, flavonoid glycosides, benzoic acids, cinnamic acids, coumarins and lignans were quantified in oregano extract. Quinic acid, naringenin, luteoline-7-O-glucoside, caffeic acid, apigenin and luteolin were the most abundant phenols detected in oregano extract