Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients With Heart Failure

Yamada, Shiro
Sakakibara, Mamoru
Yokota, Takashi
Kamiya, Kiwamu
Asakawa, Naoya
Iwano, Hiroyuki
Yamada, Satoshi
Oba, Koji
Tsutsui, Hiroyuki

Open link

Publication date

January 2013

DOI

10.1253/circj.CJ-12-1088

Publisher

Japanese Circulation Society

Abstract

Background: Adaptive servo-ventilation (ASV) improves cardiac function in patients with heart failure (HF). We compared the hemodynamics of control and HF patients, and identified the predictors for acute effects of ASV in HF. Methods and Results: We performed baseline echocardiographic measurements and hemodynamic measurements at baseline and after 15min of ASV during cardiac catheterization in 11 control and 34 HF patients. Heart rate and blood pressure did not change after ASV in either the control or HF group. Stroke volume index (SVI) decreased from 49.3±7.6 to 41.3±7.6ml/m2 in controls (P<0.0001) but did not change in the HF patients (from 34.8±11.5 to 32.8±8.9ml/m2, P=0.148). In the univariate analysis, pulmonary capillary wedge pres...