When a genetic disease-causing variant causing autosomal dominant diseases is identified, predictive DNA testing is possible for at-risk relatives to investigate whether they are carrying the familial variant. In current practice, the proband is asked to inform at-risk relatives, often supported by a family letter. This review summarizes the literature on preferences of probands and relatives regarding how and by whom at-risk relatives should be informed. A search involving digital databases (Pubmed, Medline, and PsycInfo) focusing on patient attitudes toward informing relatives at risk of autosomal dominant onco-, cardio-, or neurogenetic disease, resulted in 1,431 screened records, of which 117 full-text papers were assessed. Eventually, ...
If undetected, inherited cardiac conditions can lead to sudden cardiac death, while treatment option...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
When a genetic disease-causing variant causing autosomal dominant diseases is identified, predictive...
When a genetic disease-causing variant causing autosomal dominant diseases is identified, predictive...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current practice...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
If a hereditary predisposition to colorectal cancer or breast cancer is diagnosed, most guidelines s...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
If undetected, inherited cardiac conditions can lead to sudden cardiac death, while treatment option...
If undetected, inherited cardiac conditions can lead to sudden cardiac death, while treatment option...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
When a genetic disease-causing variant causing autosomal dominant diseases is identified, predictive...
When a genetic disease-causing variant causing autosomal dominant diseases is identified, predictive...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current practice...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
The uptake of predictive DNA testing in families with a hereditary disease is <50%. Current pract...
If a hereditary predisposition to colorectal cancer or breast cancer is diagnosed, most guidelines s...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at young age, even without prev...
If undetected, inherited cardiac conditions can lead to sudden cardiac death, while treatment option...
If undetected, inherited cardiac conditions can lead to sudden cardiac death, while treatment option...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
Introduction: In current practice, probands are asked to inform relatives about the possibility of p...
.jpg%3Fwidth%3D300&w=3840&q=75)
Add to ORKG