Emerging evidence indicates that a disruption in brain network organization may play an important role in the pathophysiology of schizophrenia. The neuroimaging fingerprint reflecting the pathophysiology of first-episode schizophrenia remains to be identified. Here, we aimed at characterizing the connectome organization of first-episode medication-naïve patients with schizophrenia. A cross-sectional structural and functional neuroimaging study using two independent samples (principal dataset including 42 medication-naïve, previously untreated patients and 48 healthy controls; replication dataset including 39 first-episode patients [10 untreated patients] and 66 healthy controls) was performed. Brain network architecture was assessed by mean...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Funder: Fundamental Research Funds for the Central Universities (2020FZZX001-05, 2019FZJD005) and Zh...
Emerging evidence indicates that a disruption in brain network organization may play an important ro...
Emerging evidence indicates that a disruption in brain network organization may play an important ro...
Previous studies suggested that the topological properties of brain anatomical networks may be aberr...
Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps onto diffuse alt...
Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps onto diffuse alt...
Schizophrenia is often regarded as a “dysconnectivity” disorder and recent work using graph theory h...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Background: White matter disruptions in schizophrenia have been widely reported, but it remains uncl...
The foundation for the studies comprising this thesis is the notion that schizophrenia's symptoms st...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Funder: Fundamental Research Funds for the Central Universities (2020FZZX001-05, 2019FZJD005) and Zh...
Emerging evidence indicates that a disruption in brain network organization may play an important ro...
Emerging evidence indicates that a disruption in brain network organization may play an important ro...
Previous studies suggested that the topological properties of brain anatomical networks may be aberr...
Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps onto diffuse alt...
Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps onto diffuse alt...
Schizophrenia is often regarded as a “dysconnectivity” disorder and recent work using graph theory h...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Emerging evidence suggests schizophrenia to involve widespread alterations in the macroscale wiring ...
Background: White matter disruptions in schizophrenia have been widely reported, but it remains uncl...
The foundation for the studies comprising this thesis is the notion that schizophrenia's symptoms st...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Dating back to the late 19th century, a longstanding hypothesis of schizophrenia is that it is a dis...
Funder: Fundamental Research Funds for the Central Universities (2020FZZX001-05, 2019FZJD005) and Zh...