Practice-dependent motor cortex plasticity is reduced in non-disabled multiple sclerosis patients
- Stampanoni Bassi M.
- Buttari F.
- Maffei P.
- De Paolis N.
- Sancesario A.
- Gilio L.
- Pavone L.
- Pasqua G.
- Simonelli I.
- Sica F.
- Fantozzi R.
- Bellantonio P.
- Centonze D.
- Iezzi E.
Publication date
January 2020
DOIAbstract
Skill acquisition after motor training involves synaptic long-term potentiation (LTP) in primary motor cortex (M1). In multiple sclerosis (MS), LTP failure ensuing from neuroinflammation could contribute to worsen clinical recovery. We therefore addressed whether practice-dependent plasticity is altered in MS
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