Purpose of the paper: Health services’ quality relies on the patients’ ability to participate in the provision of care as co-creators of value. Among others, individual health literacy - i.e. the ability to access, understand, process and use health information for the purposes of health protection and promotion - is crucial to realize the full potential of patient involvement. This paper investigates the consequences of inadequate individual health literacy on self-efficacy perception and awareness of health-related issues, which are expected to affect the process of patient empowerment. Methodology: A sample of 438 Italian patients was built. The Newest Vital Sign (NVS) was used to assess individual health literacy skills. A self-reportin...