This work verifies whether research diversification by a scientist is in some measure related to their collaboration with multidisciplinary teams. The analysis considers the publications achieved by 5300 Italian academics in the sciences over the period 2004–2008. The findings show that a scientist’s outputs resulting from research diversification are more often than not the result of collaborations with multidisciplinary teams. The effect becomes more pronounced with larger and particularly with more diversified teams. This phenomenon is observed both at the overall level and for the disciplinary macro-areas