The Role of the Patient-Prosthesis Mismatch after Aortic Valve Replacement: The Prognostic Signicance

Patient-Prosthesis Mismatch (PPM) represent a controversial issue in current clinical practice. e negative impact of PPM on patient prognosis a er aortic valve replacement has been reported in several studies showing increased all-cause and cardiac mortality. Moreover, it has been recently described the relationship between PPM and structural valve deterioration of biological prostheses. In patient at risk for PPM several issues should be considered, and in the current era cardiac surgery the preoperative planning should consider the di erent type of valve available and the di erent surgical technique that could be used to prevent it. e present editorial analyse the state of the art in term of PPM