Glioblastoma multiforme (GBM) is the most common and inevitably lethal primary brain tumor, with a median survival rate of only 15 months from diagnosis. The current standard treatment involves maximal surgical resection flanked by radiotherapy and chemotherapy with the alkylating agent temozolomide. However, even such aggressive treatment is never curative, and recurrent tumors always arise, commonly in more aggressive, chemo- and radio-resistant forms, leading to untreatable and deadly tumors. MicroRNAs, recognized major players in cancer, are deeply involved in GBM, as shown by more than a decade of studies. In this review, we revise the main milestones of MicroRNA studies in GBM, and the latest relevant discoveries in this field. Exampl...
Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment ...
Abstract Glioblastoma stem-like cells (GSCs) are critical for the aggressiveness and progression of ...
CNS tumours occur in both pediatric and adult patients and many of these tumours are associated with...
Glioblastoma multiforme (GBM) is the most common and inevitably lethal primary brain tumor, with a m...
Glioblastoma multiforme (GBM) is the most common type of malignant gliomas, characterized by genetic...
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary brain tumor. G...
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its resistance to th...
Glioblastoma (GBM) is the most common primary malignant tumor in adults, and its morbidity and morta...
Brain tumors in children and adults are challenging tumors to treat. Malignant primary brain tumors ...
Glioblastomas (GBM) are one of the most malignant adult primary brain tumors. Through decades of res...
Glioblastoma multiforme (GBM) is the most common malignant glioma. Despite innovative research effor...
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal therapy, is an...
Glioma represents a serious health problem worldwide. Despite advances in surgery, radiotherapy, che...
Abstract Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have limi...
Glioblastoma, also known as glioblastoma multiform or GBM, is the most common and most malignant pri...
Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment ...
Abstract Glioblastoma stem-like cells (GSCs) are critical for the aggressiveness and progression of ...
CNS tumours occur in both pediatric and adult patients and many of these tumours are associated with...
Glioblastoma multiforme (GBM) is the most common and inevitably lethal primary brain tumor, with a m...
Glioblastoma multiforme (GBM) is the most common type of malignant gliomas, characterized by genetic...
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary brain tumor. G...
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its resistance to th...
Glioblastoma (GBM) is the most common primary malignant tumor in adults, and its morbidity and morta...
Brain tumors in children and adults are challenging tumors to treat. Malignant primary brain tumors ...
Glioblastomas (GBM) are one of the most malignant adult primary brain tumors. Through decades of res...
Glioblastoma multiforme (GBM) is the most common malignant glioma. Despite innovative research effor...
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal therapy, is an...
Glioma represents a serious health problem worldwide. Despite advances in surgery, radiotherapy, che...
Abstract Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have limi...
Glioblastoma, also known as glioblastoma multiform or GBM, is the most common and most malignant pri...
Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment ...
Abstract Glioblastoma stem-like cells (GSCs) are critical for the aggressiveness and progression of ...
CNS tumours occur in both pediatric and adult patients and many of these tumours are associated with...