Add to ORKGIn this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal monitoring of minimal residual disease in 12 patients with All-1/AF-4 positive ALL. Of these, seven also showed at presentation a typical t(4;11) cytogenetic translocation. Seven patients were infants <18 months of age and five were adults. Eleven patients were treated with high-dose intensive induction and consolidation chemotherapy without bone marrow transplantation and one received conservative treatment due to poor performance status. Three had resistant disease, four relapsed within 12 months after achieving complete remission, and five are in continuous complete remission (CCR) at 32, 39, 52, 53 and 61 months from diagnosis, respective...
AbstractIntroductionMinimal residual disease is an important independent prognostic factor that can ...
Background: The graft-versus-leukemia effect is able to induce clinical responses in patients with c...
The study was aimed to investigate the feasibility and clinical significance of quantitative detecti...
In this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal ...
In this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal ...
Twenty-five patients (22 adults and 3 infants) with ALL1/AF4-positive acute lymphoblastic leukemia (...
We sequentially studied bone marrow (BM) samples of 25 patients in complete remission of an acute ly...
Background and Methods: The implications of the detection of residual disease after treatment of acu...
We compared quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) to qualitative R...
We compared quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) to qualitative R...
Bone marrow samples of 16 patients (two adults and 14 children) with a B lineage acute lymphoblastic...
Minimal residual disease (MRD) in patients with Philadelphia chromosome-positive acute lymphoblastic...
Hybrid fusion genes are specific tumor markers of several leukemic subtypes. The use of reverse tran...
Real-time quantitative polymerase chain reaction (RQ-PCR) is a standardized tool for minimal residua...
Bone marrow samples of 16 patients (two adults and 14 children) with a B lineage acute lymphoblastic...
AbstractIntroductionMinimal residual disease is an important independent prognostic factor that can ...
Background: The graft-versus-leukemia effect is able to induce clinical responses in patients with c...
The study was aimed to investigate the feasibility and clinical significance of quantitative detecti...
In this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal ...
In this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal ...
Twenty-five patients (22 adults and 3 infants) with ALL1/AF4-positive acute lymphoblastic leukemia (...
We sequentially studied bone marrow (BM) samples of 25 patients in complete remission of an acute ly...
Background and Methods: The implications of the detection of residual disease after treatment of acu...
We compared quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) to qualitative R...
We compared quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) to qualitative R...
Bone marrow samples of 16 patients (two adults and 14 children) with a B lineage acute lymphoblastic...
Minimal residual disease (MRD) in patients with Philadelphia chromosome-positive acute lymphoblastic...
Hybrid fusion genes are specific tumor markers of several leukemic subtypes. The use of reverse tran...
Real-time quantitative polymerase chain reaction (RQ-PCR) is a standardized tool for minimal residua...
Bone marrow samples of 16 patients (two adults and 14 children) with a B lineage acute lymphoblastic...
AbstractIntroductionMinimal residual disease is an important independent prognostic factor that can ...
Background: The graft-versus-leukemia effect is able to induce clinical responses in patients with c...
The study was aimed to investigate the feasibility and clinical significance of quantitative detecti...