The intrinsic geographical distribution and the increasing complexity are two significant properties of modern business processes (BPs) that have not been fully addressed by existing simulation tools for BP analysis. Quantitative analysis of BPs is essential both at design time, to predict the BP quality of service (QoS), and at execution time, to dynamically reconfigure the BP and guarantee the pre-agreed QoS. In this respect, this work proposes a model-driven QoS-aware framework for simulation-based quantitative analysis of BPs. Specifically, the framework adopts a distributed simulation approach that replicates the service-oriented infrastructure of a BP into the corresponding simulation infrastructure based on the HLA-Evolved standar...