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Citicoline oral solution in glaucoma: is there a role in slowing disease progression?

Ottobelli, L
MANNI, GIANLUCA
CENTOFANTI, MARCO
Iester, M
Allevena, F
Rossetti, L.

Publication date

January 2013

DOI

10.1159/000350496

Publisher

S. Karger AG

Abstract

To assess the effect of citicoline on visual field rates of progression in patients with progressing glaucoma

Extracted data

Related items

Can treatment with citicoline eyedrops reduce progression in glaucoma? The results of a randomized placebo-controlled clinical trial

L. Rossetti
M. Iester
L. Tranchina
L. Ottobelli
G. Coco
E. Calcatelli
C. Ancona
P. Cirafici
G. Manni

January 2020

Precis:Citicoline eyedrops in patients with progressing glaucoma.Purpose:This study aimed to test wh...

Evidence of the neuroprotective role of citicoline in glaucoma patients

Parisi,V
Coppola, G
Oddone, F
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Ziccardi, L
Ricci, B
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MANNI, GIANLUCA

January 2008

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Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution

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Manni G.
Roberti G.
Micera A.
Bruno L.
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Altafini R.
Quaranta L.
Agnifili L.
Tanga L.
Riva I.
Oddone F.

January 2019

Purpose To evaluate the presence and concentration of citicoline and its metabolites (choline, cytid...

Citicoline oral solution in glaucoma : is there a role in slowing disease progression?

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January 2013

PURPOSE: To assess the effect of citicoline on visual field rates of progression in patients with pr...

Oral citicoline: influence of long-term therapy on perimetric glaucoma defects

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Morphological and functional evaluation of oral citicoline therapy in chronic open-angle glaucoma patients: A pilot study with a 2-year follow-up

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Morphological and Functional Evaluation of Oral Citicoline Therapy in Chronic Open-Angle Glaucoma Patients: A Pilot Study With a 2-Year Follow-Up

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The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial

Rossetti, Luca
Goni, Francisco
Montesano, Giovanni
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Topouzis, Fotis
Romano, Dario
Galantin, Eleonora
Delgado-Gonzales, Noemi
Giammaria, Sara
Coco, Giulia
Vandewalle, Evelien
Lemmens, Sophie
Giannoulis, Dimitrios
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Manni, Gianluca

January 2023

Purpose: This study aims to evaluate whether the use of citicoline oral solution could improve quali...

The Effect of Oral Citicoline and Docosahexaenoic Acid on the Visual Field of Patients with Glaucoma: A Randomized Trial

Alfonso Anton
Virginia Garcia
Marcos Muñoz
Karla Gonzales
Eleonora Ayala
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Antonio Morilla-Grasa

September 2022

The role of nutraceuticals in the treatment of glaucoma remains controversial. The aim of this study...

Cytidine 5′-diphosphocholine (Citicoline): Evidence for a neuroprotective role in glaucoma

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Marchini G.
Caporossi A.
Scuderi G.
Tomasso L.
Brunoro A.

January 2020

Glaucoma, a heterogeneous set of progressively degenerative optic neuropathies characterized by a lo...

Can Treatment With Citicoline Eyedrops Reduce Progression in Glaucoma? The Results of a Randomized Placebo-controlled Clinical Trial

Rossetti, Luca
Iester, Michele
Tranchina, Laura
Ottobelli, Laura
Coco, Giulia
Calcatelli, Elisabetta
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Manni, Gianluca

July 2020

Precis: Citicoline eyedrops in patients with progressing glaucoma. Purpose: This study aimed to test...

Effects of oral citicoline in perimetric glaucoma defects

L. Arrico
S. Compagno
F. Pacella
D. Bianchini
C. Borrazzo
P. Turchetti
M. Malvasi
E. Trovato Battagliola
E. Pacella

January 2021

Abstract: Purpose: to study the neuroprotective effect of oral citicoline (CT) in patients with prim...

Correction of visual disturbances in patients with the primary open angle glaucoma by citicoline (CDP-Choline)

M A Frolov
N S Morozova
A M Frolov
K A Kazakova

June 2011

Purpose: to estimate the efficacy of citicolines (CDP-choline) for treatment of glaucomatous optic n...

Can treatment with citicoline eyedrops reduce progression in glaucoma? The results of a randomized placebo-controlled clinical trial

L. Rossetti
M. Iester
L. Tranchina
L. Ottobelli
G. Coco
E. Calcatelli
C. Ancona
P. Cirafici
G. Manni

January 2020

Precis:Citicoline eyedrops in patients with progressing glaucoma.Purpose:This study aimed to test wh...

Evidence of the neuroprotective role of citicoline in glaucoma patients

Parisi,V
Coppola, G
Oddone, F
Maria Angrisani, A
Ziccardi, L
Ricci, B
Quaranta, L
CENTOFANTI, MARCO
MANNI, GIANLUCA

January 2008

The glaucomatous disease is currently considered a disease involving ocular and visual brain structu...

Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution

Carnevale C.
Manni G.
Roberti G.
Micera A.
Bruno L.
Cacciamani A.
Altafini R.
Quaranta L.
Agnifili L.
Tanga L.
Riva I.
Oddone F.

January 2019

Purpose To evaluate the presence and concentration of citicoline and its metabolites (choline, cytid...

Citicoline oral solution in glaucoma : is there a role in slowing disease progression?

L. Ottobelli
G.L. Manni
M. Centofanti
M. Iester
F. Allevena
L. Rossetti

January 2013

PURPOSE: To assess the effect of citicoline on visual field rates of progression in patients with pr...

Oral citicoline: influence of long-term therapy on perimetric glaucoma defects

Arrico, Loredana
Compagno, Sabrina
Pacella, Fernanda
Bianchini, Daniele
Borrazzo, Cristian
Turchetti, Paolo
Malvasi, Mariaelena
Battagliola Trovato, Edoardo
Pacella, Elena

January 2021

Primary Open Angle Glaucoma (POAG) is characterized by a gradual loss of retinal ganglion cells (RGC...

Cytidine 51-diphosphocholine (Citicoline) in glaucoma: Rationale of its use, current evidence and future perspectives

Roberti G.
Tanga L.
Michelessi M.
Quaranta L.
Parisi V.
Manni G.
Oddone F.

January 2015

Cytidine 51-diphosphocholine or citicoline is an endogenous compound that acts in the biosynthetic p...

Morphological and functional evaluation of oral citicoline therapy in chronic open-angle glaucoma patients: A pilot study with a 2-year follow-up

Lanza Michele
Gironi Carnevale Ugo Antonello
Mele L.
Bifani Sconocchia Mario
Bartollino S.
Costagliola Ciro.

January 2019

Aims: To study the neuroprotective effect of oral citicoline (CT) therapy in primary open-angle glau...

Morphological and Functional Evaluation of Oral Citicoline Therapy in Chronic Open-Angle Glaucoma Patients: A Pilot Study With a 2-Year Follow-Up

Michele Lanza
Ugo Antonello Gironi Carnevale
Luigi Mele
Mario Bifani Sconocchia
Silvia Bartollino
Ciro Costagliola

January 2019

Aims: To study the neuroprotective effect of oral citicoline (CT) therapy in primary open-angle glau...

Cytidine 5′-Diphosphocholine (Citicoline) in Glaucoma: Rationale of Its Use, Current Evidence and Future Perspectives

Gloria Roberti

November 2015

Cytidine 5′-diphosphocholine or citicoline is an endogenous compound that acts in the biosynthetic p...

The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial

Rossetti, Luca
Goni, Francisco
Montesano, Giovanni
Stalmans, Ingeborg
Topouzis, Fotis
Romano, Dario
Galantin, Eleonora
Delgado-Gonzales, Noemi
Giammaria, Sara
Coco, Giulia
Vandewalle, Evelien
Lemmens, Sophie
Giannoulis, Dimitrios
Pappas, Theofanis
Manni, Gianluca

January 2023

Purpose: This study aims to evaluate whether the use of citicoline oral solution could improve quali...

The Effect of Oral Citicoline and Docosahexaenoic Acid on the Visual Field of Patients with Glaucoma: A Randomized Trial

Alfonso Anton
Virginia Garcia
Marcos Muñoz
Karla Gonzales
Eleonora Ayala
Estela del Mar Sanchez
Antonio Morilla-Grasa

September 2022

The role of nutraceuticals in the treatment of glaucoma remains controversial. The aim of this study...

Cytidine 5′-diphosphocholine (Citicoline): Evidence for a neuroprotective role in glaucoma

Gandolfi S.
Marchini G.
Caporossi A.
Scuderi G.
Tomasso L.
Brunoro A.

January 2020

Glaucoma, a heterogeneous set of progressively degenerative optic neuropathies characterized by a lo...

Can Treatment With Citicoline Eyedrops Reduce Progression in Glaucoma? The Results of a Randomized Placebo-controlled Clinical Trial

Rossetti, Luca
Iester, Michele
Tranchina, Laura
Ottobelli, Laura
Coco, Giulia
Calcatelli, Elisabetta
Ancona, Chiara
Cirafici, Paola
Manni, Gianluca

July 2020

Precis: Citicoline eyedrops in patients with progressing glaucoma. Purpose: This study aimed to test...

Effects of oral citicoline in perimetric glaucoma defects

L. Arrico
S. Compagno
F. Pacella
D. Bianchini
C. Borrazzo
P. Turchetti
M. Malvasi
E. Trovato Battagliola
E. Pacella

January 2021

Abstract: Purpose: to study the neuroprotective effect of oral citicoline (CT) in patients with prim...

Correction of visual disturbances in patients with the primary open angle glaucoma by citicoline (CDP-Choline)

M A Frolov
N S Morozova
A M Frolov
K A Kazakova

June 2011

Purpose: to estimate the efficacy of citicolines (CDP-choline) for treatment of glaucomatous optic n...

Can treatment with citicoline eyedrops reduce progression in glaucoma? The results of a randomized placebo-controlled clinical trial

L. Rossetti
M. Iester
L. Tranchina
L. Ottobelli
G. Coco
E. Calcatelli
C. Ancona
P. Cirafici
G. Manni

January 2020

Precis:Citicoline eyedrops in patients with progressing glaucoma.Purpose:This study aimed to test wh...

Evidence of the neuroprotective role of citicoline in glaucoma patients

Parisi,V
Coppola, G
Oddone, F
Maria Angrisani, A
Ziccardi, L
Ricci, B
Quaranta, L
CENTOFANTI, MARCO
MANNI, GIANLUCA

January 2008

The glaucomatous disease is currently considered a disease involving ocular and visual brain structu...

Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution

Carnevale C.
Manni G.
Roberti G.
Micera A.
Bruno L.
Cacciamani A.
Altafini R.
Quaranta L.
Agnifili L.
Tanga L.
Riva I.
Oddone F.

January 2019

Purpose To evaluate the presence and concentration of citicoline and its metabolites (choline, cytid...